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《Journal of Kunming Medical University》 2010-06
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General Pharmacological Study of Bifonazole Cream

KUANG Li-hua,ZHU Xu-yan,XIE Jian-zhong (The People's Hospital of Xishuangbanna State,Jinghong Yunnan 666100,China)  
Objective To study the general pharmacological action of Bifonazole cream,offer an experimental basis for clinical application.Methods The influence on sleep duration and spontaneous activity by inunctions of Bifonazole cream to mice and the change of blood pressure,heart rate,electrocardiogram,breathing frequency and range in anaesthetic rats after inunctions of Bifonazole cream were observed to estimate the effects of Bifonazole cream on nervous system,cardiovascular system and respiratory system.Results In this experiment,three dosages of Bifonazole cream and basilaris substantia had no obvious influence on sleep duration and spontaneous activity in mice. Bifonazole cream also did not evidently change the value of blood pressure,heart rate,electrocardiogram,breathing frequency and range in anaesthetic rats after inunctions.Conclusion It is suggested that Bifonazole cream has no evident effects on central nervous system,cardiovascular system and respiratory system after inunctions to animals
【CateGory Index】: R965
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