COMPARATIVE STUDY OF IN VITRO MOTILITY AND ADHESION OF HIGH AND LOW METASTATIC SALIVARY ADENOID CYSTIC CARCINOMA CELL

Shi-Hongnan;He-Rongen;Zou-Xiaojian(Dept of Oral Maxillofacial Surgery,Sclool of Stomatology,Shanghai Second Medical University,Shanghai(200011)  

tudying the in vitro motility and adhesion of tumor cell is important in understanding the invasion and metastasis mechanisms of malignant tumors.The in vitro motility of two Acc cell lines, hiqh metastatic Acc-M, strain,and Acc-2 line,was measured by Boyden chamber technique.Statistical analysis of the results showed slgnficant differences between the high and low metastatic cells.The ability of motility was higher in Acc-M than that in Acc-2. The cell adhesion test showed that Acc-M had stronger ability of adhesion than Acc-2.The result suggested in vitro motility and adhesion may play an important role in invasion and metastasis of Acc.

【Key Words】： Salivary adenoid cystic carcinoma (SAcc) Cell line Metastasis Invasion In vitro motility Adhesion
【Fund】： 国家自然科学基金
【CateGory Index】： R739.8

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