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《Journal of Comprehensive Stomatology》 2001-01
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The Comparison of T Suppressor Function at Remission and Ulcerative Stages of Patients with RAU.

HU Yan,Savage NW,Sugerman PB,et al.The stomatological hospital of Guang Dong Province,Guang Zhou 510280 [  
Objective:The aim of the current study was to investigate the ability of peripheral blood cells to mount a satisfactory level of suppressor activity.Methods:12 RAU patients at active and remission phases and 15 healthy persons were selected in this project.All subjects were taken 40 ml of venous blood at the same time on each day of experimentation.PBMC were isolated by density gradient centrifugation and divided into three fractions (AE, NE and SR).The suppressor activity at different concentration of Con A was measured by a concanavalin A generated suppressor assay system.Results:Samples obtained from 12 RAU patients and a control group showed a depression in suppressor activity in RAU patients that is disease phase related with return to normal levels in remission.Conclusion:These findings suggest that alterations in suppressor activity are not a primary event in the initiation of RAU lesions and do not have any controlling influence on the progress of individual lesions. [
【CateGory Index】: R781.5
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1 Hu Yan *, Neil W Savage, Phil B Sugerman. *The Stomatology Hospital of Guangdong Province, Guangzhou 510260;The changes of suppressor T cells function in patients with RAU[J];CHINESE JOURNAL OF STOMATOLOGY;1998-02
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