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《The Journal of clinical Pediatrics》 1998-04
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Exploration of mechanism of bovine colostrum specific antibody for lahibiting rotavirus in intestinal tract

Yu Kai-ming, Xu Yi, Huang Hai, Jiang Ming-hua. Shanghai Institute for Pediatric Research, Shanghai Second Medical University, Shanghai 200092  
Forty-three infants with rotavirus infectious diarrhea were treated with cow colostrum containing antibody against human rotavirus. Thirty-seven infants suffering from rotavirus infectious diarrhea as control group theraputed by smecta. The comparison for relationship between efficiency of antidiarrhea and viral excreting in stool was made in two groups. The results showed that the total therapeutic efficiency is 91 % and viral antigen in stool couldn't be detected in 89% after treatment in colostrum group. But the total treating efficiency is only 41% and positive rate of viral antigen in stool was 61% after administration of drug in the group of smecta therapy. It demonstrated that antirotaviral colostrum could specifically neutralize virus and inhibit viral multiplication in intestinal tract, and therefore exert the effect of then-py; while smecta only play a role of protective barrier for intestinal mucosa without specific antiviral effect.
【CateGory Index】: R725.1
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【References】
Chinese Journal Full-text Database 3 Hits
1 PENG Zhi-yong,SU Su-liang (Department of pediatrics,Chen Xinghai Hospital,Zhongshan,Guangdong,528415,China);IVIG auxiliary treatment for children's malnutrition complicated by rota-virus enteritis[J];Hainan Medical Journal;2004-04
2 ;Progress in the Treatment of Infantile Rotaviral Enteritis With TCM or Western Medicine[J];Guiding Journal of TCM;2006-02
3 YUAN Jin-song,XIE Guo-qiang,SHENG Yu-fen (Department of Clinical Laboratory, the First Affiliated Wuxi Hospital,Nanjing Medical University, Jiangsu Wuxi 214002,China);Clinical Study of Fecal Rotavirus Antigen Rapid Detection of Infant Diarrhea[J];Journal of Medern Laboratory Medicine;2004-06
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Zhao Jinming1;Qiang Boqin2;Zhao Tongxing3et al;Detection of Diarrhoea Viruses in Children with Acute Gastroenteritis[J];CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL VIROLOGY;1995-01
【Co-citations】
Chinese Journal Full-text Database 7 Hits
1 WANG Xiao-xian, LIU Shu-mei, YAO Huan-yin (The People’s Hostpital of Shaoxing, Zhejiang Province, Zhejiang Shaoxing 312000, China);To observe the efficacy of racecadotril granules in treatment of infant with rotavirus enteritis[J];Journal of Pediatric Pharmacy;2007-02
2 REN Yanli The Third Affliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Clinical Observation of Smecta in Treating Infantile Autum Diarrhea[J];Journal of Medical Forum;2004-24
3 HUANG Qiao-lian, LI Dao-pei.(Department of Pediatrics,Xiaolang People's Hospital, Zhongshan 528415, Guangdong , P. R.China);Observation on the efficacy of racecadotril in treatment of 153 infants with rotavirus enteritis[J];China Tropical Medicine;2009-03
4 WANG Rui-hua.(Department of Pediatrics,Danzhou Municipal,The Frist People's Hospital,Danzhou 571700,Hainan,P.R.Chian);Effect of Xiyanping combined with racecadotril on autumnal infantile diarrhea[J];China Tropical Medicine;2011-02
5 SUN JIAN-LAN,TONG JIAN-NING,QU MEI, et al (Department of Infection Control,The Medical & Health Center of Women and Children,Qingdao 266011,China);RELATIONSHIP BETWEEN ROTAVIRUS INFECTIONS OF MOTHER'S MILK AND ROTAVIRUS ENTERITIS OF INFANTS[J];Medical Journal of Qilu;2007-02
6 HUANG Hai-yan1 HAN Jin-xiang1 WANG Jian-wei2 GAO Xue-qin1 PAN Ji-hong1 LIU Yi1 ZHU Bo1 (1 Shandong Medical Biotechnology Center Jinan 250062,China 2 Shandong Provincial Institute of Virology Jinan 250062,China) (3 Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention Beijing 100052,China);Preliminary Study of Oligonucleotide Microarray for Detecting of Group A Rotavirus[J];Progress In Biotechnology;2005-03
7 HUANG Shuyuan,CAI Xiuquan,HUANG Haiduan;CLINICAL OBSERVATION OF TREATMENT OF ACUTE ROTAVIRAL ENTERITIS IN INFANTS WITH RACECADOTRIL GRANULES[J];Modern Hospital;2008-07
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Dong Lijuan,Shen Fange (Department of Internal,Beijing Children's Hospital,Beijing 100045);Analysis of 108 patients with infant parenteral complications of rotaviruses enteritis[J];Beijing Medical Journal;2002-03
2 Zhang Mingfa et al. (Shanxt Institute of TCM, Shanxi);Promotive Effect of Drugs Warming the Internal on the Gastrointestinal Movement and Diarrhea Caused by Medicine in Rats[J];;1988-04
3 ZHAO Yan (Institute of Nutrition and Food, NanJing Medical University, NanJing 210029);The Immunoregulation of Bovine Colostrum Crystal[J];Herbrvorous Animals;2001-03
4 Feng Mei (The Frist Peopls's Hospital Hangzhou, Zhejiang Hangzhou 310006, China);The observation of the damage of cardiomyocyte and the curative effect of high intravenous dose of vitamin C in infants with rotavirus diarrhoea .[J];Journal of Pediatric Pharmacy;2004-02
5 HU Xiao-bo~1,XIAO Zheng-xiang~2(1.Fuling Central Hospital,Chongqing Fuling 408000,China;2.The Women and Children Health Hospital of Longgang District,Shengzhen Longgang 518172,China);Clinical study of the effect of IFN-α2b and ribavirin on rotavirus enteritis[J];Journal of Pediatric Pharmacy;2006-03
6 FAN Zheng,CHEN Min,SHEN Li-ping (Yuhang Hospital Affiliated to Hangzhou Normal College,Zhejiang Hangzhou 311100,China);Observation of racecadotril granules in treating rotaviral enteritis in infants[J];Journal of Pediatric Pharmacy;2006-06
7 WANG Xiao-xian, LIU Shu-mei, YAO Huan-yin (The People’s Hostpital of Shaoxing, Zhejiang Province, Zhejiang Shaoxing 312000, China);To observe the efficacy of racecadotril granules in treatment of infant with rotavirus enteritis[J];Journal of Pediatric Pharmacy;2007-02
8 ZHOU Zhao-qun(Nanjing children's hospital,Nanjing 210008 China);Therapeutic efficacy of recombinant α-lb interferon anisodamine and folic acid treatment of infantile diarrhea caused by rotavirus[J];Hainan Medical Journal;2006-11
9 YUAN Bin,HAN Xinmin,YE Jin. Department of Pediatrics,TCM Hospital of Jiangsu Province,Nanjing 210029;Clinical observation on Canggezhixieling in treating 74 cases of infantile rotavirus enteritis.[J];Hebei Journal of Traditional Chinese Medicine;2002-10
10 SU Jie.Jiangsu Hospital of Combination of Traditional Chinese Medicine with Western Medicine,Nanjing 210028;Therapeutic effect of combination of traditional Chinese medicine with western medicine on infantile autumn diarrhea.[J];Hebei Journal of Traditional Chinese Medicine;2002-10
【Secondary References】
Chinese Journal Full-text Database 8 Hits
1 DENG Fuping CHEN Hongjun HUANG Huan Department of Children Rehabilitation,Zhuhai City Maternal and Child Care Service Centre in Guangdong Province,Zhuhai 519000,China;Epidemiology Survey of Infection of Human Rotavirus[J];China Medicine and Pharmacy;2011-12
2 YUAN Jin-song,XIE Guo-qiang,SHENG Yu-fen (Department of Clinical Laboratory, the First Affiliated Wuxi Hospital,Nanjing Medical University, Jiangsu Wuxi 214002,China);Clinical Study of Fecal Rotavirus Antigen Rapid Detection of Infant Diarrhea[J];Journal of Medern Laboratory Medicine;2004-06
3 SUN Xia;Rotavirus Enteritis Examination in Children with Acute Diarrhea[J];Journal of Applied Clinical Pediatrics;2009-03
4 CHEN Qing-shu,LI Jie,XIE Chang-xia,et al.Department of Laboratory,the First Affiliated Hospital of Bengbu Medical College,Bengbu 233004,Anhui,China;Bacteria Isolation and Drug Susceptibility Test in 480 Cases with Diarrhea[J];Chinese Journal of General Practice;2010-04
5 CHEN Xiaoling,WANG Yuling,WANG Yu,LI Yusong(The Yanbu Hospital of Nanhai District,Foshan 528247,China);Study on Effects of Agastache Rugosa Healthy Energy Dripping Pills in Treating Children with Viral Enteritis[J];Clinical Medicine & Engineering;2010-06
6 HUANG Yan,FANG Yiqian(1.Xiaotang Hospital,Nanhai District of Foshan,Guangdong Province,Foshan 528222,China;2.Xixiang People's Hospital,Bao'an District of Shenzhen,Shenzhen 518102,China);Observation of curative effect and nursing on children with group of A rotavirus diarrhea by dermal medication[J];China Medical Herald;2010-13
7 CHEN Guang-quan,ZENG Jing,ZHANG Hui-yuan,et al.Beijing Entry-Exite Inspection and Quarantine(Beijing 100026,China);Detecion of food borne vireses by gene-chip assay[J];Chinese Journal of Public Health;2008-05
8 WU Xiao-lian (Longquan People′s Hospital,Lishui 323700,China);Analysis of group A rotavirus detection in 2012 cases of infants with acute diarrhea[J];Chinese Journal of Health Laboratory Technology;2010-06
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Li Xiao-mian;Ren Zheng-yan;Zi Zi-qiang;Zhou Hong Department of Microbiology, Tianjin Medical College, Tianjin;Studies on the Small Round Virus--like Agent of Causing Neonatal Acute Gastroenteritis[J];Virologica Sinica;1989-03
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