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《JOURNAL OF CLINICAL OTORHINOLARYNGOLOGY》 1998-03
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Determination of normal values and analysis of their relation for distortion product otoacoustic emission in guinea pigs

Liang Yong; Zhong Naichuan(Department of Otorhinolaryngology,Union Hospital,Tongji Medical University,Wuhan,430022)  
In the present paper,we measured systematically the normal values of 1, 2, 4, 6 kHz distortion product otoacoustic emission (DPOAE) in guinea pigs and analyzed the relation of these values. The incidence of DPOAE in all frequencies were 100%. The amplitudes of DPOAE above 2 kHz were larger than 25 dB SPL,but the amplitude of 1 kHz was lower than one of above 2 kHz.The threshold of above 2 kHz were lower than one of 1 kHz. A trend was found that latencies of all frequencies decreases accompanied with the f_2 frequencies increasing. I/O function curves demonstrated that there was a significant relation between the amplitudes of DPOAE and the levels of primary stimuli in the statistics,that is,lower levels of primary stimuli and smaller amplitudes of DPOAE. Our results indicated that a guinea pig,whose DPOAE possessed the properties of high incidence, large amplitude and stable responsibility, was an appropriate experimental animal for studying DPOAE,In addition,this paper recommended briefly the experience about the measuring techniques for DPOAE in guinea pigs.
【CateGory Index】: R764
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【References】
Chinese Journal Full-text Database 3 Hits
1 Liang Yong;Zhong Naichuan(From the Department of Otolaryngology, Union Hospital, Tongji Medical University,Wuhan 430022);Effects of sodium salicylate on distortion product otoacoustic emission in guinea pigs[J];;1999-05
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【Citations】
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1 Liu Bo[ the Beijing Institute of Otolaryngology,Beijing 100005];Song Benbo; Liu Chan; Zhao Xiaoyang;A research for basic properties of several OAEs in normal hearing subjects[J];;1996-01
【Co-references】
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1 Peng Yong, Zi Xiao-hong,Song zhi, et al. Department of Neurology, The Xingya Third Hospital, Central South University, Changsha,410013 China;Cap Nimodipine in the Treatment of Cerebrovascular Disease:A Double-Blind Placebo-Controlled Trial[J];Journal of Chinese Physician;2002-05
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9 Peng Ruiyun, Wang Dewen, Gao Yabing et al. Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing, 100850;STUDIES ON PATHOLOGIC CHANGES OF CEREBRAL CONCUSSION AND APOPTOSIS OF NERVOUS CELLS IN WISTAR RATS[J];Medical Journal of Chinese People's Liberation Army;2002-11
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