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《JOURNAL OF CLINICAL OTORHINOLARYNGOLOGY》 2000-10
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Evaluation of the effect of streptomycin perfusion of the labyrinth in the treatment of Meniere′s disease and endolymphatic hydrops

PENG An quan 1 LU Yong de 1 REN Ji hao 1 CHEN Zhong 1 ( 1 Department of Otolaryngology, Second Affiliatd Hospital of Hunan Medical University, Changsha 410011)  
Objective:To investigate the clinical effect of streptomycin perfusion of the labyrinth (SPL) in the treatment of Meniere's disease.Method:13 patients with Meniere′s disease and 3 patients with delayed endolymphatic hydrops (DEH) underwent SPL. The follow-up time was between 5 and 7 years (average 6.3 years). Result:Vertigo was completely controlled in 9 patients, substantialy controlled in 4, limitedly controlled in 2 and not controlled in 1.Hearing was improved in 1 patients, stabilized in 5 and worse in 10. Tinnitus was improved in 3 patients, stabilized in 5 and worse in 8.Conclusion:SPL is a safe and effective method in the treatment of Meniere′s disease and DEH, but the hearing may be insulted and tinnitus may be worse in some patients.
【CateGory Index】: R764
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