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《Journal of Clinical Otorhinolaryngology Head and Neck Surgery》 2011-16
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Individual management of Meniere's disease and evaluation of functional outcome

CHEN Ying YANG Jun WU Hao HUANG Qi WANG Zhaoyan ZHANG Zhihua(Department of Otorhinolaryngology-Head and Neck Surgery,Xinhua Hospital Affiliated Shanghai Jiaotong University School of Medicine,Ear Institute of Shanghai Jiaotong University School of Medicine,Shanghai,200092,China)  
Objective:To investigate individual management for Meniere's disease and analyze outcomes of non-surgical and surgical management of Meniere's disease.Method:Patients with Meniere's disease were staged according to hearing and quality of life.The individual management according to the staging was established,including outpatient treatment(lifestyle change,medical management and intratympanic steroids),endolymphatic sac decompression or drainage,vestibular neurectomy and labyrinthectomy.The characteristics of patients who underwent surgical management were analyzed.The functional outcomes of surgery in dizziness,hearing loss and quality of life were evaluated for 12-month postoperative follow-up.Result:Twenty patients underwent intratympanic injection of dexamethasone.Dizziness improved in 70%(14/20),tinnitus improved in 41%(7/17),and aural fullness improved in 36%(4/11).There were 55 patients who underwent surgical managements for 57 times.Endolymphatic sac decompression or drainage was carried out in 27 patients for 28 times,vestibular neurectomy in 26 patients and labyrinthectomy in 3 patients.Vertigo control rate was 75% in patients with endolymphatic sac decompression or drainage,100% in vestibular neurectomy and 100% in labyrinthectomy at 12-month postoperative follow-up.Conclusion:The non-surgical management and endolymphatic sac decompression or drainage can improve vertigo and ameliorate quality of life.Vestibular neurectomy and labyrinthectomy are effective surgical managements to eliminate vertigo.The management of Meniere's disease depends on several factors: stages of vertigo and hearing,quality of life,surgical contraindications and subjective desire.Therefore,the management for Meniere's disease must be individualized for each patient.
【CateGory Index】: R764.33
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 SUN Xialing REN Jihao LU Yongde YIN TuanfangWU Weijing TANG Yueying HU Binya(Department of Otolaryngology,the Second Hospital of Xiangya Medical College,Central South University,Changsha, 410011,China );Round window catheter placement with dexamethasone perfusion for intractable sudden sensorineural hearing loss[J];Journal of Clinical Otorhinolaryngology Head and Neck Surgery;2007-04
2 YANG Jun1 HUANG Li1 SHI Jun1 LI Yun1 WU Hao1 KONG Weijia2(1Department of Otorhinolaryngology-Head and Neck Surgery,Xinhua Hospital,Shanghai Jiaotong University School of Medicine,Shanghai Jiaotong University School of Medicine Ear Institute,Shanghai,200092,China;2Department of Otorhinolaryngology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology);The effect of intratympanic dexamethasone or methylprednisolone on treatment of sudden sensorineural hearing loss[J];Journal of Clinical Otorhinolaryngology Head and Neck Surgery;2010-13
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Shao Jun,Guo Guang-wei,Su Ji-ping(Department of Otolaryngology and Head and Neck Surgery,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China);Methylprednisolone of Intratympanic Injection for Refractory Sudden Sensorineural Hearing Loss[J];Guangxi Medical Journal;2009-06
2 ZHANG Ping~1 WU Hao~1 YANG Jun~1 HOU Dongming~1 ZHANG Shunguo~2 CHEN Jie~1(~1Department of Otorhinolaryngology and Head-neck Surgery,Xinhua Hospital,Shanghai Second Medical University,Shanghai,200092,China;~2Department of Clinical Pharmacology,Xinhua Hospital affiliated Shanghai Second Medical University);Methylprednisolone pharmacokinetics in perilymph and plasma of guinea pig after topical administration and intracardial injection[J];Journal of Clinical Otorhinolaryngology;2005-22
3 REN Jihao LU Yongde YIN Tuanfang LIU Bin GE Yilin (Department of Otolaryngology, the Second Hospital of Xiangya Medical College, Central South University, Changsha, 410011, China);Intratympanic dexamethasone injections for intractable sudden sensorineural hearing loss[J];Journal of Clinical Otorhinolaryngology;2006-05
4 SHI Jun YANG Jun WU Hao XUE Bin CHEN XiangpingCAO Rongping MENG Guozhen XIANG Mingliang HUANG Qi(Department of Otolaryngology-Head and Neck Surgery,Xinhua Hospital,Shanghai Jiaotong University,Shanghai,200092,China);Intratympanic dexamethasone medication for suddensen sorineural hearing loss: clinical evaluation[J];Journal of Clinical Otorhinolaryngology;2006-16
5 SUN Xialing REN Jihao LU Yongde YIN TuanfangWU Weijing TANG Yueying HU Binya(Department of Otolaryngology,the Second Hospital of Xiangya Medical College,Central South University,Changsha, 410011,China );Round window catheter placement with dexamethasone perfusion for intractable sudden sensorineural hearing loss[J];Journal of Clinical Otorhinolaryngology Head and Neck Surgery;2007-04
6 YU Yuejin1 LU Zhicheng2 ZHANG Hongwen1 CAO Yunhong1 JIA Xiuhua1 HUANG Wei1 HAO Yanan1(1Department of Otorhinolaryngology,Shanghai No.7 People's Hospital,Shanghai,200137,China;2 Department of Laboratory Medicine,Shanghai No.7 People's Hospital);Association between anti-endothelial cell antibody and response to dexamethasone in sudden hearing loss[J];Journal of Clinical Otorhinolaryngology Head and Neck Surgery;2011-04
7 YANG Jun,WU Hao,HOU Dong-ming,CHEN Jie,ZHANG Ping (Department of Otolaryngology-Head & Neck Surgery,Xinhua Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200092,China);Pharmacokinetic profiles of corticosteroid in perilymph and plasma after systemic and transtympanic administration[J];Journal of Shanghai Jiaotong University(Medical Science);2007-01
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9 Cao Wei,Qiu Jianxin,Zhang Kunling,et al(Dept of Otolaryngology-Head & Neck Surgery,The First Affiliated Hospital of Anhui Medical University,Hefei 230022);Intratympanic methylprednisolone medication for intractable sudden sensorineural hearing loss[J];Acta Universitatis Medicinalis Anhui;2007-05
10 WANG Ya-lin,WANG Yin-feng.(Department of E.N.T.,Anhui Provincial Hospital,Anhui Medical University,Hefei 230001,China);Preclinical and Clinical Study of Steroid Hormone in Treating Inner Ear Disease by Intratympanic Administration[J];Medical Recapitulate;2008-19
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 LU Yongde REN Jihao WU Weijing YIN Tuanfang YANG Xinming XIE Dinghua (Department of Otorhinolaryngology, the Second Hospital of Xiangya Medical College,Central South University,Changsha, 410011,China);Intratympanic dexamethasone injections for intractable Meniere's disease[J];Journal of Clinical Otorhinolaryngology;2004-07
2 HOU Dongming 1 WU Hao 1 YANG Jun 1 ZHANG Ping 1 ZHANG Shunguo 2 CHEN Jie 1 ( 1Department of Otorhinolaryngology-Head and Neck Surgery,Xinhua Hospital,Shanghai Second Medical University,Shanghai,200092,China; 2Department of Clinical Pharmacology, Xinhua Hospital, Shanghai Second Medical University);Dexamethasone pharmacokinetics in perilymph of guinea pig after different topical administrations[J];Journal of Clinical Otorhinolaryngology;2005-07
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