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《Journal of Clinical Radiololgy》 2005-11
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Analysis of CT Perfusion in Nasopharyngeal Cancer, Inflammatory and Scar Structure

PAN Aizhen, WEI Guangyu, GAN Yi,et al. Department of Radiology, No.1 People's Hospital, Foshan, Guangdong Province 528000, P. R. China  
Objective To evaluate the value of CT perfusion in the diagnosis of nasopharyngeal cancer, inflammation and scar structure. Materials and Methods 66 cases were performed with multi-detector CT perfusion study on nasopharynx, including 20 cases in control group, 25 cases with nasopharyngeal cancer, 11 cases after radiotherapy (without recurrence alter 0.5 -5 years), and 10 cases of inflammation. TTP, BF, BV, MTT and PS were analyzed with deconvolve algorithm. All data were analyzed slaislically by paired t test. Results BF, PS and BV value of nasopharyngeal cancer group were distinctly higher than others with statistically significance. There was no statistical significance in MTT value between nasopharyngeal group and other groups. Compared with control group, BF value of inflammatory group had statistical significance. No statistical significance was found in all perfusion index between control group and post-radiation therapy group. Conclusion Primarily CT perfusion study could evaluate nasopharyngeal cancer with significantly BF, PS, and BV value, which could make differential diagnosis with inflammatory, post-radiation therapy scar structure. BF value in inflammatory group is obviously higher than that in normal tissue.
【Fund】: 2004北美放射年会RSNA,佛山市自然科学研究基金资助
【CateGory Index】: R739.63
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