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《Journal of Clinical Radiology》 2006-03
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Preliminary Study of Multi-slice CT Perfusion in Preoperative Evaluation of Meningioma Subtype

LING Huawei, DING Bei, ZHANG Huan,et al. Department of Radiology, Ruijin Hospital of Shanghai Second Medical University, Shanghai 200025, P. R. China  
Objective To evaluate the value of CT perfusion in preoperative assessment of different meningioma subtypes.Materials and Methods 17 patients of meningiomas verified by surgery and pathology were underwent with conventional MR and multislice CT perfusion. All cases were divided into three groups according to the different pathological types of meningiomas. CT data were transferred to online working station and processed to obtain time density curves, color perfusion maps and perfusion parameters, including cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT) and permeability surfaces (PS) in tumoral parenchyma, necrosis and peritumor brain edema. Perfusion values were analyzed statistically by using SPSS software.Results The CBV, CBF, MTT and PS of meningiomas were significantly higher than those of contralateral normal brain tissue in each groups. Furthermore, a significant difference in CBV, PS and CBF was found in meningothelial, angiomathous and fibroblastic types of meningiomas, no significant difference in MTT was found in different types of mengingiomas.Conclusion CT perfusion can be served as a useful method to provide hemodynamic information both for differentiation of the subtype of meningiomas and management planning before operation.
【CateGory Index】: R739.45
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