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《Journal of Clinical Radiology》 2007-06
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The Difference between rCBF and rCBV of Astrocytomas and Its Clinical Significance

ZHANG Tonghua,HU Chunhong,WU Qingde,et al.Center of Medical Imaging,The First Affiliated Hospital of Suzhou University,Suzhou,Jiangsu Province 215006,P.R.China  
Objective To compare the difference between rCBF and rCBV of astrocytomas and explore its clinical significance.Materials and Methods Both conventional and perfusion CT were performed in 29 patients with pathologically confirmed astrocytomas(15 cases in Ⅰ-Ⅱ grade,14 cases in Ⅲ-Ⅳ grade).The time-density-curves(TDC)were obtained,and cerebral blood flow(CBF)maps and cerebral blood volume(CBV)maps were generated,the rCBF and rCBV of the region of interest(ROI)were compared.Results 24 astrocytomas exhibited match between rCBF and rCBV,5 astrocytomas were mismatched with reduced rCBF and preserved or increased rCBV in ROI.Conclusion The difference between rCBF and rCBV in some area of astrocytomas is existed,rCBV and rCBF can be more useful in preoperative assessment of histological grading in astrocytomas and monitoring therapy effect.
【Fund】: 江苏省医学重点人才基金资助项目(编号:RC2003096);; 江苏省科技厅社会发展项目(编号:BS2003630)
【CateGory Index】: R739.4
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