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《JOURNAL OF CLINICAL STOMATOLOGY》 1998-03
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The Suppressive Effect of Gypenosides On Neck Lymph Node Metastasis Cell Line Derived FromHuman Oral Squamous Cell Carcinoma In vitro

Yan Junfeng; Li Jin rong; et al.(Stomatological College of Hu Bei Medical University, Wu Han, 430070.)  
The suppressive effect of gypenosides (GP) on GNM cell was studied by MTT assay andelectromicroscope. The results demonstrated the growth of GNM cell was inhibited by different GPconcentration, inhibitive rates were correlated with GP concentration. Mitochondria and rough endoplasmie reticulum were destroyed when 20Ong/m1 GP concentration was added on GNM cell. The re-search shows GP is valuable in application for treatment and prerention of metastatic cancer.
【Fund】: 湖北省自然科学基金!9521
【CateGory Index】: R739.8
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【References】
Chinese Journal Full-text Database 1 Hits
1 Yan Junfeng, Li Jinrong, Hu Zhuanzheng. College Stomatology, Hubei Medical University,430079;The Suppressive Effect of Gypenosides and Pinyangmycin on Neck Lymph Node Metastatic Cell Line Derived from Human Oral Squamous Cell Carcinoma in Vitro.[J];JOURNAL OF COMPREHENSIVE STOMATOLOGY;1999-04
【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 BI Yun-chen et al (School of Life Science,Shandong Normal University,Jinan,Shandong 250014);Research Advances on Antimicrobial Components in Leguminosae Plants[J];Journal of Anhui Agricultural Sciences;2009-09
2 Yan Junfeng, Li Jinrong, Hu Zhuanzheng. College Stomatology, Hubei Medical University,430079;The Suppressive Effect of Gypenosides and Pinyangmycin on Neck Lymph Node Metastatic Cell Line Derived from Human Oral Squamous Cell Carcinoma in Vitro.[J];JOURNAL OF COMPREHENSIVE STOMATOLOGY;1999-04
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 ZHOU Yu-bi et al (Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Xining,Qinhai 810001);Effect of BSA on RAPD Analysis of Cynomorium songaricum[J];Journal of Anhui Agricultural Sciences;2007-28
2 SHEN Hong-wei et al(College of Biological & Food Engineering,Dalian Polytechnic University,Dalian,Liaoning 116034);Study on the Optimum Extraction Condition of Gypenosides[J];Journal of Anhui Agricultural Sciences;2008-04
3 XU Xian-xiang,XIA Lun-zhu (Dept of Phar,The First Affiliated Hospital of Anhui College of Traditinal Chinese Medicine,Hefei 230031,China);Determination of emodin in gandouling tablets by TLC-scanning[J];Anhui Medical and Pharmaceutical Journal;2005-01
4 ZHAO Bin,GE Jing-fang,LI Jun(School of Pharmacy,Anhui Medical University,Hefei 230032,China);Advances in studies on the anti-tumor mechanisms of camptothecin[J];Anhui Medical and Pharmaceutical Journal;2006-01
5 TU Shui ping* , JIANG Shi hu, QIAO Min min, WANG Li fu, ZHANG Shu, YUAN Yao zong, WU Yun li,WU Yu xin. Department of Gastroenterology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025,P.R.China;Induction of apoptosis by trichosanthin in gastric cancer cell MKN-45[J];Chinese Journal of Cancer;2000-12
6 LUO Hui ling1* , CAI Ti yu1, CHEN Qiao lun1, HUANG Min quan2, MEI Cheng en1, LI Yong qiang1 1.Cancer Institute,Cancer Center, Sun Yat sen University of Medical Sciences, Guangzhou 510060, P.R.China 2.South China Institute of Botany,the;Enhancement of dendrobium candidum polysaccharide on killing effect of LAK cells of umbilical cord blood and peripharal blood of cancer patients in vitro[J];Chinese Journal of Cancer;2000-12
7 JIANG Ying li, SONG Jin dan* Key Laboratory of Cell Biology, Ministry of Public Health, China Medical University, Shenyang 110001, P.R.China;Apoptotic Induction of Xinjiang Shikonin on Human Colorectal Cancer CCL229 Cell[J];Chinese Journal of Cancer;2001-12
8 Liu Jian-Bo1, Gao Xue-Gang1, Lian Tao1, Zhao Ai-Zhi2, Li Kai-Zong2 1.Department of Surgery,Jingyang Hospital, Jingyang,Shaanxi,713700, P.R.China 2.Department of Hepatobiliary Surgery,Xijing Hospital,The Fourth Military Medical University, Xian,Shaanxi,710032, P.R.China;Apoptosis of Human Hepatoma HepG2 Cells Induced by Emodin In Vitro[J];Chinese Journal of Cancer;2003-12
9 He Chengwei Liang Nianci Mo Lier, et al.Medical Biochemistry Institute, Guangdong Medical College, Zhangjiang 524023;The effect of a diterpenoid isolated from pteris semipinnata on the HL-60 cell cycle and its enhanced in vitro cytotoxicity by anticancer drugs[J];CHINESE JOURNAL OF CANCER;1998-03
10 ZHANG Jin,WANG Chang-jun,XIE Jiang,CHEN Fang(Faculty of Pharmacology,Bengbu Medical College,Bengbu 233030,China);Protective effect of gypenosides on adriamycin induced acute cardiotoxicity in rats[J];Journal of Bengbu Medical College;2007-04
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 TANG Ting~1,YUAN Hui-ning~2,MA Jian-ping~3(1.Dept.of Pharmaceutical Analysis,Medicine and Health Management College;2.Function Laboratory,Dept.of Basic Medicine;3.Clinical Medical Colleg,Hangzhou Teachers College,Hangzhou,Zhejiang 310036,China);The preliminary study on extraction technology of gynosaponins[J];Journal of Hangzhou Teachers College(Medical Edition);2006-01
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