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《Journal of Clinical Stomatology》 2007-04
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Effects of fluid shear stress on the proliferation and cell cycle of rat osteoblasts in vitro

WU Dan,DING Yin,WANG Qi.Department of Orthodontics,College of Stomatology,Fourth Military Medical University,Xi'an 710032,China  
Objective:To observe the effect of fluid shear stress(FSS)on the cellular proliferation and cell cycle of rat osteoblasts(OBs).Method:After rat osteoblasts were stimulated by the FSS,MTT assay and flow cytometry were appli-ed to measure the cellular proliferation and cell cycle.Result:60 min FSS treatment accelerated cell proliferation significontty.24 hrs after FSS stimulation,the percentage of phase S cells(14.67±1.18)% was increased 82.2% as compared to that of the control group(8.05±1.08)%(p0.01).Conclusion:FSS plays a positive role in promoting the cellular proliferation of the rat osteoblasts.
【CateGory Index】: Q27
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