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《The Journal of Clinical Anaesthesiology》 2005-09
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Preventive effect of ambroxol on postoperative respiratory complications in elderly patients undergoing upper abdominal surgery

Luo Wenjie,Xue Qingsheng.Department of Anesthesiology,The People's Hospital of Putuo District,Shanghai 200060 CHINA  
Objective To observe the preventive effect of ambroxol on postoperative respiratory complications in elderly patients.Methods Forty elderly patients(age≥60 years,ASA Ⅰ-Ⅱ)undergoing upper abdominal surgery under general anesthesia were randomly allocated into ambrosol group(n=20)and control group(n=20).In ambrosoxol group,150mg of ambroxol was administered intravenously during anesthesia of induction,and the same volume of normal saline was given in control group.The degrees of cough,easy extend of expectoration,amount of sputum,sputum properties after operation were recorded.SpO_2 at 24h after surgery and the atelectasis were also observed.Results There were significant differences in the severity of cough,ability of expectoration amout of sputum,sputum properties(P0.01)between two groups.SpO_2 of 24h after surgery was higher in ambroxol group than that in control group.Conclusion Ambroxol is effective in the prevention of postoperative respiratory complications in surgical elderly patients.
【CateGory Index】: R619
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