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《The Journal of Clinical Anesthesiology》 2006-05
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Effect of positive end-expiratory pressure on arterial oxygenation during pneumoperitoneum

Chen Yanping, Cao Dequan, Chang Yetian.Department of Anesthesiology, Second Xiang Ya Hospital, Central South University, Changsha 410011 CHINA  
Objective To investigate the effect of positive end-expiratory pressure (PEEP) on arterial oxygenation and hemodynamics during pneumoperitoneum.Methods Twenty ASA Ⅰ-Ⅱ patients undergoing suprarenal gland mass resection and nephrectomy laparoscopically were randomly allocated to two groups with 10 cases each.The patients in group P, a constant PEEP of 5 cmH_2O was applied, while those in group C, no PEEP was applied during mechanical ventilation.Aterial blood gas and hemodynamics were recorded at the following time points: before pneumoperitoneum (T_0), at 10min (T_1), 30min (T_2), 1h (T_3)and 2h(T_4) into pneumoperitoneum.Results PaO_2 tended to increase during pneumoperitoneum in group P, while to decrease in group C, and was lower in group C than group P at T_3-T_4.Changes of MAP and HR were less than 11% in both groups. Conclusion A PEEP of 5 cmH_2O improves arterial oxygenation during pneumoperitoneum without depression of hemodynamics.
【CateGory Index】: R614
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