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《Clinical Misdiagnosis & Mistherapy》 2007-11
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Effects of Ambroxol on Pespiratory Complications after Heart Operation under Cardiopulmonary Bypass

SUN Peng-fei,SHI Ju-tong,HAN Ke,WEI Zhen-yu(Department of Cardiothoracic Surgery,Affiliated Yantai Yuhuangding Hospital Qingdao University Medical College Shandong Yantai 264000,China)  
Objective: To observe the effects of ambroxol(Mucosolvan) on reducing respiratory complications after heart operations under cardiopulmonary bypass.Methods:One hundred patients were randomly divided into the ambroxol group(studied gruop) and Bikeping group(control group).Each group consisted of fifty patients.2~14d after treatment,density of phlegm,difficulty in expectoration,pneumonic rales,respiratory complications and side effects of drugs were observed and compared.Results:The prevalence of high density of phlegm,difficulty in expectoration and pneumonic rales were markedly less in the studied group than in the control(P0.05).The prevalence of atelectasis in the studied group was 4%,much lower than that in the control group 14 %(P0.05).No obvious side effects were found in the two groups.Conclusion:Administration of ambroxol in patients after heart operations under cardiopulmonary bypass can reduce the respiratory complications,especially atelectasis.
【CateGory Index】: R654.2;R56
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Lu quan,zhang lingen,wang ying,che datian,wang libo,xiao jie.shanghai chIldren's hospital,shanghai200040;Randomized contrast trial on the therapeutical effect of oral mucosolvan syrUp[J];临床儿科杂志;2003-01
【Co-citations】
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1 SHAO Zhengyang;LIAN Junlan;HE Fei;ZHAN Lu;Pediatrics Department,Zhejiang Provincial Hospital of Integrated Chinese and Western Medicine;;Efficacy of Kechuan Koufuye on Lung Function for Children with Bronchiolitis[J];中华中医药学刊;2015-11
2 ZHANG Ya-nan;ZHANG Wei-bing;TIAN Xiao-yan;ZHANG Hui;ZHAO Chun-yu;Li Xiang;LIU Chang-ping;The Fourth Affiliated Hospital of Harbin Medical University;;Effects of different doses of ambroxol on cytokines in sputum from elderly patients with AECOPD[J];山东医药;2014-29
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5 CHENG Tian-gui(Hubei Pharmaceutical Research Institute Co.,Ltd.,Wuhan 430061);Preparation and quality control of ambroxol hydrochloride buccal tablets[J];中南药学;2009-03
6 ZHANG Ping,GUO Te-liu,XU Ya-hong,et al.(Department of Pediatrics,PLA 452nd Hospital,Chengdu 610061,China);Therapeutic Observation of Nebulized Mucosolvan in Children Bronchiolitis[J];华西医学;2008-05
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8 SUN Peng-fei,SHI Ju-tong,HAN Ke,WEI Zhen-yu(Department of Cardiothoracic Surgery,Affiliated Yantai Yuhuangding Hospital Qingdao University Medical College Shandong Yantai 264000,China);Effects of Ambroxol on Pespiratory Complications after Heart Operation under Cardiopulmonary Bypass[J];临床误诊误治;2007-11
9 HE Yue, LIAN Jun-Lan. Department of Pediatrics, Traditional Chinese Medicine and Western Medicine Hospital of Zhejiang Province, Hangzhou 310003, ZheJiang,China.;Clinical observation of Qingfei Yin (清肺饮)for treatment of children with bronchiolitis[J];中国中西医结合急救杂志;2007-05
10 ;Supplementary Therapy with Pulmicort Respules and Ambroxol Driven by Oxygen for Asthmatic Suffocating Pneumonia in Children[J];现代诊断与治疗;2007-02
【Secondary Citations】
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1 Luo weici,et al.Peking Union Medical College Hospital;A CLINICAL STUDY ON MUCOSOLVAN[J];中国新药杂志;1992-05
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