Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Clinical Cardiology》 2009-05
Add to Favorite Get Latest Update

Research the relationship between the changes of the hemodynamics of intrarenal arterial with the levels of ET-1,CGRP in essential hypertensive patients with early renal damaged

XUE Li LIU Zejun OUYANG Yingchun WEI Zongde(Department of Cardiology,Affiliated Hospital,Luzhou Medical College,Luzhou,646000,China)  
Objective:To study the relationship between the changes of hemodynamics of intrarenal arterial and the levels of ET-1,CGRP in plasma of the essential hypertensive patients (EH).Method:Ninety patients with mild to moderate EH were divided into EH patients with early renal damaged and EH patients without early renal damaged groups according to the level of blood α1-microglobulin,β2-microglobulin and urineβ2-microglobulin scale (b α1-MG20 mg/L and/or b β2-MG3 550 μg/L and/or u β2-MG154 μg/L,n=45; b α1-MG≤20 mg/Land/or b β2-MG≤3 550 μg/L and/or u β2-MG≤154 μg/L n=45); were divided into two groups according to their clinical blood presure (CBP) scale (systolic blood pressure [SBP]140-159 mmHg and/or diastolic blood presure [DBP] 90-99 mmHg n=46; SBP 160-179 mmHg and/or DBP 100-109 mmHg n=44),with 43 health as control group. Vs,Vd,Vm,AT,PI and RI of both sides of MRA,SRA and IRA were measured by Color Doppler echocardiography and all parameter of hemodynamics were decided by means of both sides intrarenal arterial while the levels of ET-1,CGRP and in plasma were measured by enzyme linked immunoscorbent assay(ELISA).Result:Compared with the control group,Vs,Vd and Vm of both sides of MRA in the EH patients were significantly lower(P0.05),AT were not significantly prolonged (P0.05) and PI,RI were highter(P0.05); Vs,Vd and Vm of both sides of SRA and IRA in the EH patients were significantly lower (P0.05),AT were significantly prolonged(P0.05),PI,RI were highter (P0.05) and Vs,Vd,Vm were lower,AT were prolonged and PI,RI were highter with the grade of clinical blood pressure (CBP) were up. Compared with the EH patients without early renal damaged group,Vs,Vm and Vd of both sides of SRA and IRA in the EH patients with early renal damaged group we significantly lower (P0.05),AT were significantly prolonged(P0.05) and PI,RI were highter (P0.05). Compared with the control group,the levels of ET-1 in plasma of the EH patients were significantly highter (P0.01) and CGRP were significantly lower(P0.01). Compared with the group of EH patients without early renal damaged,the levels of ET-1 in plasma of the group of EH patients with early renal damaged were significantly highter (P0.001) and CGRP were significantly lower (P0.01),There were significantly negative correlation between ET-1 and Vs,Vd,Vm of MRA、SRA and IRA; between CGRP and PI,RI,AT of MRA,SRA and IRA; between CGRP and Vs,Vd,Vm of MRA,SRA and IRA,especially Vd,RI of IRA.Conclusion:When the EH patients with early renal damaged,the hemodynamics of intrarenal arterial had obvious changed. The highter of the levels of ET-1 and the lower of CGRP may be the one reason of the changes of hemodynamics of intrarenal arterial in EH patients with early renal damaged.
【CateGory Index】: R544.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 5 Hits
1 XU Rui ZHOU Liaosheng LOU Zimo XING Qicong DU Wenxian (Department of Cardiology,Qianfoshan Hospitial of Shandong Province,Ji′nan 250014);The evaluation of early renal damage in essential hypertension by ultrasound Doppler renal blood flow measurement[J];Journal of Clinical Cardiology;2001-02
2 XU Rui 1 ZHOU Liaosheng 1 ZHANG Yun 2 LOU Zimo 1 XING Qicong 1 DU Wenxian 1 LEI Lei 1 ( 1Department of Cardiology, Qianfoshan Hospital of Shandong Province, Ji'nan 250014; 2Department of Cardiology, Shandong University Qilu Hospital);The factors on early renal damage in hypertensive patients[J];Journal of Clinical Cardiology;2003-09
3 YE Ji-xian 1,LI Hong-mei 1,HUANG Jing 1,ZHAO Lian-you 2 (1 Department of Cardiology, 323 Hospital of PLA,Xi'an,Shaanxi 710054,China);The effect of calcitonin gene-related peptide on vasoconstriction induced by arginine vasopressin[J];Chinese Heart Journal;2003-06
4 Liang Chunxiang; et al(General hospital of Jinan Command,PLA);Color Doppler Study on Hemodynamics of the Normal Adult Intrarenal Artery[J];CHINESE JOURNAL OF ULTRASOUND IN MEDICINE;1995-02
5 XU Rui, ZHOU Liaosheng,LOU Zimo, et al. Department of Cardiology, Qianfoshan Hospitial of Shandong Province, Ji'nan 250014, China;The predictive study of early renal damage in essential hypertension by Doppler ultrasound renal blood flow measurement[J];CHINESE JOURNAL OF UITRASONOGRAPHY;2000-10
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 DING Bi-yun,SHAO Zheng-bin,ZHENG Lin,LIN Yan-lin,XU Juan,XU Hong-qiang (The First Hospital Affiliated to Anhui College of Traditional Chinese Medicine,Anhui Hefei230031,China);Study on the Relationship between Early Nephritic Injures by Essential Hypertension and Traditional Chinese Medicine Syndrome Patterns[J];Journal of Anhui Traditional Chinese Medical College;2006-04
2 Zhao Baozhen;Zhao Yuhua ;Weng Sanchuan;Zhang Qi;Chen Chuijing;Wu Shiying;Wang Ersong;Shao Wenyu;Wang Liancai; Liu Yue;Zhu Keming;Xiong Yuanchang (Department of Ultrasound,Changhai Hospital,Second Military Medical University, Shanghai,200433);Measurement of left arteriorenal hemodynamics changes during intracardiac operation under direct vision by transesophageal color Doppler imaging[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1996-01
3 YU Lin;CAO Yu - rong Department of Ultrasound,Affilated Hospital of Hubei Institute for Nationalitics,Enshi 445000,China;Study of the Blood Flow of Renal Artery in Patients with Type 2 Diabstes Mellitus Using Doppler color Flow Imaging[J];Journal of Hubei Institute For Nationalities Medical Edition;2004-02
4 ZHANG Ning\+1, WANG Zhi\+2, ZHENG Jing\+2, et al (1.Department of Ultrasonic, 2.Department of Nephrology, The People's Hospital of Fujian Province, Fuzhou\ 350004, China) \ \;Detection of Renal Hemodynamic Changes in Patients with Primary Nephrotic Syndrome by Doppler Ultrasonography[J];Journal of Fujian Medical University;2002-04
5 Zhang Ning,Wang Zhi,Zheng Jing,et al.Department of Ultrasound,Nephralpaty. The peoples Hospital of Fujian province,Fuzhou,350004,China;Research on Relations between Renal Blood Flow of Nephrotic Syndrome and pathological Types[J];Fujian Meidical Journal;2002-06
6 Liu Xiaying Gu Xibing Xu Yueqin etc(Wuxin prefecture hospital for infectious disease control of Jiangshu province,Wuxi 214005);Study on effect of sodium unrestricted diet and sodium restricted diet on cirrhosis ascites.[J];Journal of Nurses Training;2007-22
7 Liu Xueling,Lei Pei,Zhang Lanhua First Hospital of Guangxi College of TCM(Nanning 530023);Measurement of changes of renal blood flow in hypertension with color Doppler speed energy graph[J];Guangxi Medical Journal;2003-03
8 Zhang Jie, Zhao Xunping, Zhang Xiaobing,et al Department of Urology,First Affiliated Hospital,Hubei Medical University,Wuhan 430060,China;Influence of Hydronephrosis on Renal Circulation Flowing Kinetics before and after Operation[J];JOURNAL OF HUBEI MEDICAL UNIVERSITY;2000-04
9 GAO Fu yuan 1 WANG Cun long 1 ZHANG Ting ji 1 ZHANG Zhi hong 1 WANG Li ming 1 SUN Yun chai 1 ( 1Department of Urology,the Affiliated Tangshan workders Hospital Hebei Medical University,Tangshan,Hebei,063000);Changes in intrarend vascular resistance index and the levels of NAG and GAL before and after ESWL[J];JOURNAL OF CLINAICAL UROLOGY;2000-03
10 ZHU Ying-hui1,GAO Xiu-lin2(1.Department of Nephrology,Shijingshan Hospital,Beijing 100043,China;2.Department of Leaders' Health and Care,Fuxing Hospital Affiliated toCapital University of Medical Sciences,Beijing 100038,China);The Changes of Renal Arterial Resistive Index in Early Stage of Renal Injury Following Hypertension[J];Practical Clinical Medicine;2008-03
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 Wu Hongchao 1,Qian Xuexian 1,Li Liping 2 1Department of Cardiology, 2Department of Gastroenterology, 2Zhujiang Hospital,First Military Medical University,Guangzhou 510282;Effects of calcitonin gene related peptide on the cardiac function of stunned myocardium[J];;1999-04
2 YE Ji xian 1,LI Hong mei 1,HUANG Jing 2,YANG Chun jiao 1,LI Min 3 (1 Department of Cardiology,No.323 Hospital of PLA,Xi'an Shaanxi 710054,China);Changes in plasma calcitonin gene-related peptide and endothelin concentration in patients with essential hypertension[J];Chinese Heart Journal;2001-03
3 Li Hongmei, Pei Jianming, Zhu Miaozhang, Niu Guobao and Zang Yimin Department of Physiology, Fourth Military Medical University, Xi′an 710032;Antiarrhythmic effect of calcitonin gene related peptide[J];;1997-01
4 Jin Chunxiang; Xu Guangbo(The First Hospital,Baiqiuen Medical University);Duplex Color Doppler Evaluation of Renal Arterial Blood Flow in Different phases of Hypertension[J];CHINESE JOURNAL OF ULTRASOUND IN MEDICINE;1995-01
5 XU Rui, ZHOU Liaosheng,LOU Zimo, et al. Department of Cardiology, Qianfoshan Hospitial of Shandong Province, Ji'nan 250014, China;The predictive study of early renal damage in essential hypertension by Doppler ultrasound renal blood flow measurement[J];CHINESE JOURNAL OF UITRASONOGRAPHY;2000-10
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved