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《Chinese Journal of Clinical Gastroenterology》 2002-03
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The Characteristics of Intestinal Flora in Patients with Liver Cirrhosis and its Therapeutic Observation

Niu Ming hua, Zou Xiao ping, Gao Feng, et al Department of Gastroenterology, Ankang Railroad Hospital, Xi an 725000  
Purpose: To observe the characteristics of intestinal flora in patients with liver cirrhosis and to evaluate the therapeutic effect on these bacteria. Methods: Microculture technique and common primer PCR were employed to identify the features of intestinal flora in 177 patients with liver cirrhosis and 30 healthy controls. The bacterial morphological examination was used to observe the formation and aggregation of bacteria in the stool and several drugs were used to evaluate the therapeutic effect on these bacteria. Results: The aggregation rate of bacteria in the stool was significantly higher in patients with liver cirrhosis than in the healthy controls(51.4% vs 7.8%,P0 01), furthermore, the generative ability, mobility and resistance to antibiotics remarkably increased in patients with liver cirrhosis. After the patients with liver cirrhosis were treated with bifid triple viable capsule, duphalac and combined both of them, the aggregation rates were 60.1%, 51.2% and 10.7% respectively, significantly decreased as compared with placebo 100%(P0 05). Conclusion: The aggregation rate of bacteria, the generative ability, activity, resistance to bacteria were significantly higher in patients with liver cirrhosis than in healthy controls. Bifid triple viable capsule and duphalac, as medicine for regulation of the intestinal flora, have better effects than antibiotics.
【CateGory Index】: R575.2
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Chinese Journal Full-text Database 2 Hits
1 Zhao Caiyan,Liu Jinxing,Zhen Zhen,et al.Third Hospital of Hebei Medical University,Shijiazhuang 050051;Changes and correlation of serum IL-2、sIL-2R、IL-6、T subsets in patients with liver cirrhosis and hepatocellular carcinoma[J];CHINESE JOURNAL OF PRACTICAL INTERNAL MEDICINE;1999-01
2 LIANG Houjie , LIN Jinqian, XU Qiwang, et al Department of Gastroenterology Southwest Hospital, Third Military Medical University, Chongqing 400038, China;A study on the formation and regulation of cryptic growth cells of the intestinal flora in patients with liver cirrhosis[J];CHINESE JOURNAL OF INTERNAL MEDICINE;2000-04
Chinese Journal Full-text Database 10 Hits
1 Li Dongye,Wu Ling(Heilongjiang Bayi Agriculture University,Daqing 163319);Research of Ruminant Probiotics[J];Journal of Heilongjiang Bayi Agricultural University;2011-01
2 WANG Li-sheng1,LI Ying-xue1,WEI Xiao-xia1,XUN An-ying1,ZEN Wei-sen2,MA Xiao-dong3,ZHU Hui-ming1,LUO Shen-qiu2(1.Department of Gastroenterology,the Second Clinical Medical College,Jinan University,Shenzhen 518020,China;2.Department of Cytobiology,Southern Medical University,Guangzhou 510515,China;3.Center Laboratory,Southern Medical University,Guangzhou 510515,China);Influence of whole peptidoglycan of Bifidobacterium on the mitochondrial membrane potential of mouse peritoneal macrophages[J];Current Immunology;2008-06
3 REN Zhi-jie 1, WU Yun-lin 1, ZHANG Chen-li 1, ZHANG Shu 1, FENG Li 2 (1. Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China; 2. Minhang Hospital of Shanghai Ruijin Hospital (Group), Shanghai 201100, China);Clinical effects of Duphalac on blood ammonia level and results of number connection test of patients with liver cirrhosis[J];Shanghai Journal of Preventive Medicine;2001-06
4 Liu Junkang et al.(Research Center of Biological Wave, The Third Militare Medical University, Chongqing 400038);SELF-LIMITED GROWTH,RHYTHM AND GRAN MOVEMENT OF BACTERIA[J];JOURNAL OF MICROBIOLOGY;1999-04
5 Yan-Zi Gou, Jian-Qi Lian, Qing-He Nie, Yan Zhuang, Qing-Quan Liu, Bin Shao, Center of Diagnosis and Treat- ment for Infectious Diseases of Chinese PLA, Tangdu Hos- pital, the Fourth Military Medical University, Xi’an 710038, Shaanxi Province, China;Clinical signif icance of Toll-like receptor 4 and 2 expression on the surface of peripheral blood mononuclear cells in patients with liver cirrhosis[J];World Chinese Journal of Digestology;2006-34
6 WANG Li-sheng, YANG Lin, LI Ying-xue, ZHU Zhong-sheng, XUN An-ying, ZHU Hui-ming(Dept of Gastroenterology, The Second Clinical Medical Hospital,Ji′nan University,Shenzhen,Guangdong 518020,China);Regulation of whole peptidoglycan of Bifidobacteria on ERK of rat peritoneal macrophages[J];Chinese Pharmacological Bulletin;2007-05
7 LUO Ming yu, WANG Xiao bing [WT5”BZ](Teaching Hospital,Wuhan Univeristy of Science and Technology ,Wuhan 430062,China);Clinical Study in the Treatment of Post hepatitis Cirrhosis with An Hua Pill[J];JOURNAL OF WUHAN YEJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY;2000-02
8 GONG Shi (The People's Hospital of Gaozhou City, Gaozhou 525200, China);Study on the level changes of cholesterol, cholesteryl ester and cholinesterase of patients with severe hepatitis[J];China Medical Herald;2010-08
9 Zheng Mubai,He Yuanliu,Pan Quan,et al Dezhou People's Hospital in Shandong Province,Dezhou,Shandong 253014 China;Regional Cell Immune Response on Ultrasound Guided Superantigen Injection After Anhydrous Ethanol Injection Therapy for Hepatocellular Carcinoma[J];Chinese Journal of Ultrasound in Medicine;2007-10
10 ZHU Zhong-sheng,WANG Li-sheng,YANG Lin,ZHU Hui-ming,LAI Zhuo-sheng,JIANG Bo,PAN Ling-jia,ZHOU Dian-yuan(Department of Gastroenterology,Shenzhen People's Hospital,the Second Clinical Medical University,Jinan University,Shenzhen 518020,China);Influence of whole peptidoglycan of Bifidobacteria on NF-kB of macrophages[J];Chinese Journal of Microecology;2006-02
China Proceedings of conference Full-text Database 1 Hits
1 ;肝硬化患者外周血单核细胞表面TLR4、TLR2表达及临床意义[A];[C];2007
Chinese Journal Full-text Database 10 Hits
1 LI Xiu liang, GAOYong xiang, ZHOUShu fang, et al Clinical Medicine College, Chengdu University of Traditional Chinese Medicine (Chengdu,610075,China);Influence on Yi-yuan Zhi-xie Granules to Intestines Flora of Diarrhea due to Spleen Asthenia Mice[J];Journal of Chengdu Unversity of Tarditional Chinese Medicine;2001-03
2 FAN Dong-xu,YANG Ting,FANG Shu-qing,LUO Wei,WANG Yue-sheng (General Surgery of the First Affiliated Hospital of Jiamusi University,Jiamusi 154003, China);The relationship between serum endotoxin level and intestinal flora in cirrhotic patients[J];Heilongjiang Medicine and Pharmacy;2005-01
3 GUO Yin-yan(Haidian Hospital,Beijing 100080);A clinical study of glutamine therapy in lower albuminemia patients with liver cirrhosis[J];Chinese Journal of Clinical Hepatology;2007-06
4 LIN Jinqian, LIANG Houjie;Disorder or intestinal bacterial flora and its treatment in cirrhosis[J];JOURNAL OF CLINICAL INTERNAL MEDICINE;2000-02
5 LIANG Xue(Department of Gastroenterology,First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning 530023,China);Observation of Medilac-s joint levofloxacin capsule in the treatment of acute infectious diarrhea[J];Internal Medicine of China;2009-04
6 LI Xiao-ling,HUO Li-juan(Dept of Gastroenterology,First Clinical Medical College,Shanxi Medical University,Taiyuan 030001,China);Protective effect of glutamine on liver function in hepatic cirrhosis patients[J];Journal of Shanxi Medical University;2009-02
7 Zhao Caiyan,Liu Jinxing,Zhen Zhen,et al.Third Hospital of Hebei Medical University,Shijiazhuang 050051;Changes and correlation of serum IL-2、sIL-2R、IL-6、T subsets in patients with liver cirrhosis and hepatocellular carcinoma[J];CHINESE JOURNAL OF PRACTICAL INTERNAL MEDICINE;1999-01
8 LU Lungen. Department of Gastroenterology,Renji Hospital,Shanghai Jiaotong University School of Medicine Shanghai Institute of Digestive Disease,Shanghai(200001);Endotoxin Receptors,Endotoxemia and Liver Cirrhosis[J];Chinese Journal of Gastroenterology;2007-07
9 MEI Ai-min1,SONG Li-gang2,WANG Rui-ting1,ZHANG Shu-hui3(1.Chengde medical college,Hebei Chengde 067000,China;2.The Affili ated Hospital of Chengde Medical College,Hebei Chengde 067000,China;3.The Peo ple's Hospital of Hebei Province,Hebei Shijiazhuang 067000,China);The effect of bifid triple viable to endotoxemia and some cytokines of liver cirrhosis patients[J];Chinese Journal of Hospital Pharmacy;2005-01
10 ZHAO Longfeng, LI Hong, HAN Dewu. (Department of Infectious Diseases, First Hospital of Shanxi Medical University, Taiyuan 030001, China);Effects of intestinal endotoxemia on the development of cirrhosis in rats[J];Chinese Journal of Hepatology;2001-S1
【Secondary References】
Chinese Journal Full-text Database 4 Hits
1 Wang Li,Li Jiabin,Ma Yong,et al.the First Clinical Institute of Anhui Medical University,Hefei 230032,Anhui Province,China Corresponding author:Li Jiabin,E-mail:lijiabin948@vip.sohu.com;The effect of lipopolysaccharides on hepatic vascular pathologic changes in chronic hepatitis B[J];Journal of Clinical Hepatology;2012-01
2 Yan Lan, Zhang Jundong(Department of Pharmacology, School of Pharmacy, Second Military Medical University, Shanghai,200433);Development of Birid Triple Viable (BIFICO) for clinical application[J];Shanghai Medical & Pharmaceutical Journal;2007-03
3 SUN Xiaohui Department of Gastroenterology,Yuyao City People's Hospital in Zhejiang Province,Yuyao 315400,China;The Effects of Probiotics on Intestinal Flora and Cell-mediated Immune Function in Patients with Liver Cirrhosis[J];China Modern Doctor;2011-18
4 LI Shangyong SUN Gang WANG Jiadi WANG Yongjie Medical Department, the First People's Hospital of Siping City in Jilin Province, Siping 136001, China;The effect observation of lactulose combined with live combined bacillus subtilis and enterococcus faecium enteric-coated capsules (Medlic-S) in the treatment of patients with mild hepatic encephalopathy after hepatic cirrhosis[J];China Modern Medicine;2012-34
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
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