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《JOURNAL OF LINYI MEDICAL COLLEGE》 2000-03
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THE EFFECT OF ALBIZA CORTEX ON IMMUNE FUNCTIONS OF MICE

Wang Faquan, Zheng Weidong, Ma Chunling, et al (Department of Pathogenic Biology,Linyi Medical College,Linyi 276002)  
Objective To study the effect of albiza cortex on the immune functions of mice. Methods The stomachs of mice were perfused with albiza cortex extractive fluid which effect was equal to the doses of 10mg/(kg.d),100mg/(kg.d) and 500mg/(kg.d) of the crude drugs for 6 days continuously to assay the phagocytic rate and index of abdominal macrophages of the mice phayocytizing chicken red blood cell (CRBC) and the induced level of tumor necrosis factor (TNF) and interleukin-2 by using concanvalinA (ConA) to activate the abdominal macrophages and splenic lymphocytes.Results It was found that the phagocytic rate, the phagocytic index and the induced level of TNF of the abdominal macrophages of the mice perfused with 100mg/(kg.d) of albize cortex increased by 11.6%,18.7% and 17.3%(P0.05) respectively over the control group,those of the mice perfused with 500mg/(kg.d) of albiza cortex increased by 19.4%,28.6% and 26.9%(P0.01) respectively over the control group,and the induced level of IL-2 of the splenic lymphocytes of the mice perfused with 500mg/(kg.d) of albiza cortex increased by 17.2%(P0.05) over the control group.Conclusion Albiza cortex can improve the immune functions of mice.
【CateGory Index】: R285
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