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《Chinese Clinical Oncology》 2009-10
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A random study of xiaoaiping injection combined with chemotherapy on the treatment of advanced non-small cell lung cancer

WANG Wen-yu,ZHOU Yun,ZHANG Xiao-ju,GAO Tian-hui,LUO Zhi-fen,LIU Ming-yue.Department of Medical Oncology,Henan Province People's Hospital,Zhengzhou 450003,China  
Objective:To evaluate and compare the efficacy and safety of xiaoaiping injection combined with chemotherapy and chemotherapy alone on the treatment of patients with advanced non-small cell lung cancer(NSCLC).Methods:Patients with advanced NSCLC were randomly divided into trial group(27 patients)and control group(29 patients).Chemotherapy with TP regimen was given to the all patients.Meanwhile,a regimen of 80ml/d xiaoaiping injection was given from the lst to 7th days on the chemotherapy cycle in the trial group as well as the control patients received chemotherapy alone.Twenty-one days were as a cycle and all patients with 2 cycles.Results:The response rate was 63.0%(17/27) in the trial group and 51.7%(15/29) in the control group(P0.05).The KPS score after treatment was 86.20±9.65 in the trial group as well as 80.11±8.91 in the control group,and the difference of improvement was significant(P0.05).NK cells decreased(P0.05)in control group and it changed slightly in treatment group.The adverse effects related to xiaoaiping injection were mild and didn't need any treatment.Conclusion:Xiaoaiping injection combined with chemotherapy are better than chemotherapy alone on the treatment of NSCLC.It can increase the sensitivity to chemotherapy and improve the quality of life and NK cells immunity function of the patients with advanced NSCLC.
【Fund】: 河南省重点攻关课题基金资助项目(0623060900)
【CateGory Index】: R734.2
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【References】
Chinese Journal Full-text Database 1 Hits
1 CHEN Qiangsong,YANG Zejiang,OU Wu,et al.Department of Oncology,Hepu County Hospital of Traditional Chinese Medicine,Guangxi Zhuang Autonomous Region,Hepu 536100;Effect of Shenmai injection combined with chemotherapy on quality of life of patients with advanced non-small cell lung cancer[J];Hebei Journal of Traditional Chinese Medicine;2010-10
【Citations】
Chinese Journal Full-text Database 4 Hits
1 Wang Zhiliang;Fan Qingxia;Fan Kuisheng(Depertment of Onclolgy,the First Affiliated Hospital,Henan Medecal Universyty,Zhengzhou 450052);Clinical study of Xiaoaiping in the treatment of cancer[J];JOURNA OF HENAN MEDICAL UNIVERSITY;1994-01
2 LI Maoquan, SHEN Jianhua, XU Bing, et al. Department of Radiology, Shanghai East Hospital, Shanghai 200120, China;The Mechanism of laboratory research for xiaoaiping treating SGC 7901 gastric carcinoma cellular strains[J];Journal of Interventional Radiology;2001-04
3 HUANG Zhen-qian,TAN Huo,WANG Chun-yan,ZHANG Huan-zhu,LIU Dan,ZHOU Cheng-zhi,LIU Xin.Center of Oncolog & Hematology,the First Affiliated Hospital,Guangzhou Medical College,Guangzhou 510230,China;Clinical research of combined xiaoaiping injection with chemotherapy on advanced non-small cell lung cancer[J];Chinese Clinical Oncology;2007-02
4 HU Chi ding (Department of Oncology, Wuhan 6th Hospital, Wuhan 430015, China);Xiaoaiping in Treatment of 33 Patients with Advanced Stage Malignant Tumor[J];Herald of Medicine;2001-10
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CHEN Tong-sheng1,WANG Xiao-ping2,WANG Zhi-ping3,WANG Long-xiang1, WANG Hui-ying1,XING Da11.MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science,South China Normal University,Guangzhou 510631,China2.Department of Anesthesiology,The First Affiliated Hospital of Ji'nan University,Guangzhou 510632,China3.Science and Technology Park Ltd.,Guangzhou University of TCM,Guangzhou 510445,China;Fluorescence Emission Analysis of Caspase-3 Activation Induced by Xiao-Ai-Ping(XAP) inside Living Human Lung Adenocarcinoma Cells[J];Spectroscopy and Spectral Analysis;2008-06
2 Wang Zhiliang;Wang Guiji;Yue Bangyi(Clinical Cooperation Group of Xiaoaiping Of Henan Province, Zhengzhou 450052);Clinical Studies of Chinese Herb Marsdenia Tenacissia in the Treatment of Advanced Esophageal and Gastric Cancer (A Report of 112 Cases)[J];HENAN JOURNAL OF ONCOLOGY;1995-03
3 Wang Zhiliang;Fan Qingxia;Fan Kuisheng(Depertment of Onclolgy,the First Affiliated Hospital,Henan Medecal Universyty,Zhengzhou 450052);Clinical study of Xiaoaiping in the treatment of cancer[J];JOURNA OF HENAN MEDICAL UNIVERSITY;1994-01
4 LI Maoquan, SHEN Jianhua, XU Bing, et al. Department of Radiology, Shanghai East Hospital, Shanghai 200120, China;The Mechanism of laboratory research for xiaoaiping treating SGC 7901 gastric carcinoma cellular strains[J];Journal of Interventional Radiology;2001-04
5 WU Wen-juan~1*, ZOU Ying-hua~2, MA Rong-zhen~1, ZHONG Zhi-wei~1, LIU Xiang-dong~1, LI Hai-tao~1, YANG Chun~3, CUI Hui-xian~3(1.Department of Radiology, the Third Hospital of Hebei Medical University, Shijiazhuang 050051, China; 2.Department of Medical Imaging, Peking University First Hospital, Beijing 100034, China; 3. Department of Anatomy, Hebei Medical University, Shijiazhuang 050017, China);Apoptosis, proliferation and angiogenesis of tumor cells after TACE treatment with As_2O_3 and Lipiodol[J];Chinese Journal of Interventional Imaging and Therapy;2005-04
6 XING Wang-xing 1,CHENG Rong-zhen 3, CHENG Bin 2, MI He-ming 2, WU Yu-tian 2 (1.The 117th Hospital of PLA, Hangzhou 310013, China; 2. Hangzhou Jianfeng Dekang Pharmaceutical Limited Company, Hangzhou 311422,China; 3.College of Pharmacy, Second Military Medical University,Shanghai 200433,China);Discrimination of Common Confounding Species of Wuguteng[J];Research and Practice of Chinese Medicines;2004-01
7 HUANG Zhen-qian,TAN Huo,WANG Chun-yan,ZHANG Huan-zhu,LIU Dan,ZHOU Cheng-zhi,LIU Xin.Center of Oncolog & Hematology,the First Affiliated Hospital,Guangzhou Medical College,Guangzhou 510230,China;Clinical research of combined xiaoaiping injection with chemotherapy on advanced non-small cell lung cancer[J];Chinese Clinical Oncology;2007-02
8 LI Hui,YE Qing,YIN Xiao-jin,LI Yun-man.College of Pharmacy,China Medicine University,Nanjing 210009,China;The research of angiogenesis in hepatocellular carcinoma[J];Chinese Clinical Oncology;2009-04
9 SAIFUDING Keyoumu,QU Yuan-li,TANG Yong.The 4th Department of Medical Oncology,the Affiliated Tumor Hospital of Xinjiang Medical University,Urumchi 830011,China;Clinical observation of domestic gemcitabine combined with nedaplatin in advanced non-small cell lung cancer[J];Chinese Clinical Oncology;2009-11
10 WANG Xin1,LI Ke1,LIN Na1,FAN Qing-xia1,ZHENG Yu-ling2(1.Department of Oncology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,Henan,China;2.Henan College of Traditional Chinese Medicine,Zhengzhou 450000,Henan,China);Effects of Ginsenoside Rg3 on Growth and VEGF,bFGF Expressions of Transplanted Human Lung Squamous Cell Carcinoma in Nude Mice[J];Liaoning Journal of Traditional Chinese Medicine;2010-02
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 Wang Zhiliang;Fan Qingxia;Fan Kuisheng(Depertment of Onclolgy,the First Affiliated Hospital,Henan Medecal Universyty,Zhengzhou 450052);Clinical study of Xiaoaiping in the treatment of cancer[J];JOURNA OF HENAN MEDICAL UNIVERSITY;1994-01
2 LI Maoquan, SHEN Jianhua, XU Bing, et al. Department of Radiology, Shanghai East Hospital, Shanghai 200120, China;The Mechanism of laboratory research for xiaoaiping treating SGC 7901 gastric carcinoma cellular strains[J];Journal of Interventional Radiology;2001-04
3 WT4”BX]SUN Jue,SHEN Jian hua, ZHU Mei hua,LI Chao heng, FAN Zhong ze [WT4”BX]Central Hospital of Pu Tuo District [WT5HZ];Experimental Study on Therapeutic Function of “Carcinoma Eliminating Injection” on Cell of Human Gastric Carcinoma[J];ACTA UNIVERSITATIS TRADITIONIS MEDICALIS SINENSIS PHARMACOLOGIAEQUE SHANGHAI;2000-02
4 Yuan Xiuying Fang Zhongze and Huang Xiuying (Central Hospital of Putuo District ,Shanghai,200012);Observations on the treatment of 14 cases of advanced gastric cancer with Inj. Xiao-Ai-Ping[J];Shanghai Medical & Pharmaceutical Journal;1996-06
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