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《Chinese Clinical Oncology》 2010-08
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Application value of 128-slice four-dimensional spiral CT whole-brain perfusion imaging in brain tumors

ZENG Wen-bing,WANG Ming-quan,WANG Yi,WU Jiong,LUO Jiang-pin,WEN Yun,LUO Shao-ming,WANG Jun-yan.Department of Radiology,Wanzhou Three Gorges Central Hospital,Chongqing 404000,China  
Objective To evaluate the diagnostic value and the clinical significance of 128-slice spiral CT whole-brain perfusion imaging in brain tumors.Methods The whole-brain CT perfusion(CTP) imaging data of 36 patients with brain tumor confirmed surgically and pathologically were analyzed retrospectively.A Siemens 128-slice spiral CT scanner was used to perform the whole-brain CTP imaging.A perfusion analysis software was used to obtain time-density curves(TDC),and observe the tumorous and contralateral brain tissular blood flow(CBF),blood volume(CBV),time to peak(TTP),and capillary permeability surface(PS) values.The difference between the simple axis images and the entire brain images was evaluated,and these CTP parameters were analyzed statistically.Results The average visual rating scores of whole-brain perfusion images were significantly higher than that of axial perfusion images in all cases(t=-11.852,P=0.000),and the whole-brain perfusion images were more precise in positioning a brain tumour.Different types of brain tumors have their own different characteristics TDCs,which were made for their differential diagnosis.The trend high-grade gliomas showed up speed downhill-type,and while the meningiomas and metastatic tumors showed a speed up slow down-type.Statistics analysis indicated that there was significant difference(P0.01) between tumorous and contralateral brain tissue,and among the three types of brain tumorous perfusion parameters(CBF,TTP and PS).Conclusion 128-slice spiral CT perfusion imaging combination of enhanced CT scan can be used to evaluate blood perfusion of the whole human brain,and make preoperative overall assessment and precise positioning for brain tumors.The TDCs and perfusion parameters can be used for quantitative analysis and identifing the category of the brain tumors.
【Fund】: 重庆市卫生局和万州区科委攻关课题(200903030)
【CateGory Index】: R739.4
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【References】
Chinese Journal Full-text Database 1 Hits
1 ZENG Wen-bing1,WANG Yi2,WANG Ming-quan1,WU Jiong1,LIU xing-hua1,LUO Jiang-ping1,WEN Yun11.Department of Radiology,Wanzhou Three Gorges Central Hospital,Chongqing 404100,P.R.China2.Department of Radiology,Third Affiliated Hospital & Research Institute of Surgery,Third Military Medical University,Chongqing 400042,P.R.China;Evaluation of 128-slice spiral CT whole brain perfusion imaging in grading infiltrating astrocytomas[J];Journal of Medical Imaging;2011-09
【Citations】
Chinese Journal Full-text Database 4 Hits
1 ZHANG Jing, QI Jianpin, CHENG Lang, et al. Department of Radiology, The Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430030, P. R. China;Evaluation of Tumor Vessel Permeability in Cerebral Neoplasm with Multi-slice Helical CT Perfusion Imaging[J];Journal of Clinical Radiololgy;2004-08
2 LING Huawei, DING Bei, ZHANG Huan,et al. Department of Radiology, Ruijin Hospital of Shanghai Second Medical University, Shanghai 200025, P. R. China;Preliminary Study of Multi-slice CT Perfusion in Preoperative Evaluation of Meningioma Subtype[J];Journal of Clinical Radiology;2006-03
3 LEI Zheng, WEI Li, WANG Zhiming,et al. Department of Radiology, No.1 Affiliated of Jinzhou Medical College, Jinzhou, Liaoning Province 121001, P. R. China;Application Value of Multi-slice CT Perfusion Imaging in Brain Tumors[J];Journal of Clinical Radiology;2007-03
4 HUANG Biao, LIANG Chang-hong, ZHANG Yun-ting, ZHOU Dong, LIN Hua-huan, RU Guang-teng, LIU Hong-jun, LIU Qi-shun(Department of Radiology, Guangdong Provincial People’s Hospital, Guangzhou 510080,China);The Correlative Study Between CT Perfusion Imaging and Microvascular Density of Astrocytoma[J];Journal of Practical Radiology;2005-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LI Zhi-yong,GE Ying,LIU Jing-hong,WANG Ke-li,WU Jian-lin(Department of Radiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China);Preliminary clinical evaluation of CT perfusion imaging of stomach neoplasm[J];Journal of Dalian Medical University;2008-04
2 JIANG Shan-shan,LI Yang-bin,TAN Li-lian,CHEN De-ji(Department of Radiology,Second Affiliated Hospital,Guangzhou Medical College,Guangzhou 510260,China);Preliminary Study of Perfusion Imaging in Cerebral Neoplasms with MSCT[J];Academic Journal of Guangzhou Medical College;2007-01
3 YIN Long-lin, YANG Zhi-gang,LI Yuan, LI Zhen-lin, YU Jian-qun, BAI Hong-li. Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China;Preliminary Study of Tumor Perfusion Assessment with Multidetector CT in Carcinoma of Esophagus and Cardia[J];Journal of Sichuan University(Medical Science Edition);2008-05
4 MA Zhi-wen,DONG Dan-dan,HAN Xue(Department of CT Room,The First Clinical College,Harbin Medical University,Harbin 150001,China);Diagnosis and classification of astrocytic tumors by multi-slice CT perfusion imaging[J];Journal of Harbin Medical University;2007-02
5 QUO Xing,YU Lei, DING Wei,et al.Department of Radiology,Peace Hospital,Changzhi Medical College,Changzhi,046000,China.;Diagnostic value of various perfusion CT parameters in prediction of classification of astrocytoma in brain[J];Chinese Imaging Journal of Integrated Traditional and Western Medicine;2010-05
6 CHEN Jiansheng, LIU Yulin, CHEN Xian,et al. Department of Radiology, Hubei Province Cancer Hospital, Wuhan 430079, P. R. China;Multi-slice CT Perfusion of Nasophargeal Carcinoma[J];Journal of Clinical Radiololgy;2005-08
7 HUANG Biao, LIANG Changhong, ZHANG Yunting, et al. Department of Radiology, Guangdong Provincial People′s Hospital, Guangzhou,Guangdong Province 510080, P. R. China;Correlation Study Between CT Perfusion and Tumor Microvascular Density in Rabbit VX2 Soft-tissue Tumor[J];Journal of Clinical Radiololgy;2005-08
8 LING Huawei, DING Bei, ZHANG Huan,et al. Department of Radiology, Ruijin Hospital of Shanghai Second Medical University, Shanghai 200025, P. R. China;Preliminary Study of Multi-slice CT Perfusion in Preoperative Evaluation of Meningioma Subtype[J];Journal of Clinical Radiology;2006-03
9 LEI Zheng, WEI Li, WANG Zhiming,et al. Department of Radiology, No.1 Affiliated of Jinzhou Medical College, Jinzhou, Liaoning Province 121001, P. R. China;Application Value of Multi-slice CT Perfusion Imaging in Brain Tumors[J];Journal of Clinical Radiology;2007-03
10 Kang Xiao-li,He Ning (Department of Radiology,Second Hospital of Lanzhou University,Lanzhou 730030,China);Application of multislice spiral CT perfusion imaging and molecular pathology in the diagnosis of renal cell carcinoma[J];Journal of Lanzhou University(Medical Sciences);2009-02
【Co-references】
Chinese Journal Full-text Database 2 Hits
1 HUANG Biao, LIANG Chang-hong, ZHANG Yun-ting, ZHOU Dong, LIN Hua-huan, RU Guang-teng, LIU Hong-jun, LIU Qi-shun(Department of Radiology, Guangdong Provincial People’s Hospital, Guangzhou 510080,China);The Correlative Study Between CT Perfusion Imaging and Microvascular Density of Astrocytoma[J];Journal of Practical Radiology;2005-05
2 ZHANG Jia-wen1, FENG Xiao-yuan1, LIU Bin2, et al1 Department of Radiology, Huashan Hospital,Fudan University2 Department of Radiology, The First Affiliated Hospital of Anhui Medical University;Using 64-slice CT Perfusion Imaging Permeability Surface to Evaluate the Histopathologic Grade of Intracranial Gliomas[J];Chinese Computed Medical Imaging;2008-01
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 ZHANG Dong, XU Weibang, ZOU Liguang,et al. Department of Radiology, The Affiliated Xinqiao Hospital, No.3 Military Medical University, Chongqing 400037, P.R.China;Correlation of Dynamic CT Indices with VEGF Expression in Brain Astrocytoma[J];Journal of Clinical Radilolgy;2002-02
2 ZHANG Jing, QI Jianpin, CHENG Lang, et al. Department of Radiology, The Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430030, P. R. China;Evaluation of Tumor Vessel Permeability in Cerebral Neoplasm with Multi-slice Helical CT Perfusion Imaging[J];Journal of Clinical Radiololgy;2004-08
3 LING Huawei, DING Bei, ZHANG Huan,et al. Department of Radiology, Ruijin Hospital of Shanghai Second Medical University, Shanghai 200025, P. R. China;Preliminary Study of Multi-slice CT Perfusion in Preoperative Evaluation of Meningioma Subtype[J];Journal of Clinical Radiology;2006-03
4 PU Jun-zhi,ZHI Yan,GE GEN Tuo-ya,GUAN Li-jun,MEI Xiao-fang,LIU Jun(Department of CT,the First Hospital of Huhhot 010020,Innermogolie,China);A Comparative Study Between Pathology and CT Classified Patterns and Diagnosis of the Golioma of the Brain (A Report of 70 Cases)[J];Journal of Practical Radiology;2002-09
5 DU Wei -qing,DENG Jing -lan,HUAN Yi,WANG Jing,GE Ya-li,YANG Chun-min,YANG Yan,CHANG Ying-juan(Department of Radiology,Xijing Hospital, the Fourth Military Medical University, Xi’an 710032,China);Correlative Study of MR Perfusion Weighted Imaging with Histopathologic Grade in Gliomas[J];Journal of Practical Radiology;2004-05
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