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《Chinese Journal of Clinical Pharmacy》 2001-03
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Inhibitory effects of gynostemma pentaphyllum on lipid peroxidation reaction in rats liver

Tao Jianwu, Yao Caiping, Wang Jichun, Hao Guangli, Ye Zhengjun (The Central Laboratory,Hubei College of Pharmacy and Medical Laboratory Technology,Wu Han 430064)  
AIM: To observe inhibitory effects of gynostemma pentaphyllum (GP) on liver lipid peroxidation caused by carbon tetrachloride (CCl 4). METHODS: Wistar rats were randomly divided into 4 groups: A (control); B (CCl 4); C (GP); D (CCl 4+GP). RESULTS: The content of lipid peroxide (LPO) increased and the vitality of glutathione peroxidase (GSH Px) decreased in CCl 4 group compared with the control group. The lipid peroxidation caused by CCl 4 was inhibited by administering GP simultaneously. CONCLUSION: The results indicate that GP could decrease liver injury induced by CCl 4.
【CateGory Index】: R965
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