Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Labour Medicine》 2002-05
Add to Favorite Get Latest Update

Subchronic Toxicity of Paraphenylenediamine(PPD) Oxidants to Mice after Cutaneous Exposure

YUAN Hui,PU Yue pu,YIN Li hong,LI Yun hui (School of Public Health,Southeast University,Nanjing 210009,China)  
To study the subchronic toxicity to mice caused by the oxidized product of paraphenylenediamine(PPD). The mixture of paraphenylenediamine(PPD) and H 2O 2 (the main ingredient of oxidized hair dyes and its oxidant) is appiled on to the skin of Balb/c mice,once per three days,for a month. During the testing period,the growth of mice was observed. Meanwhile, following items were detected,including biochemical examination of blood,histopathology of liver,spleen and kidney and genotoxicity. It is shown that the genotoxicity was observed in the mouse bone marrow cells and the functions of liver and kidney were affected by the oxidized product of PPD. [Conclusion] The results suggcsted that there were potential risks to health when using oxidized hair dyes frequently.
【Fund】: 江苏省卫生厅预防医学科研基金 (Y2 0 0 2 0 1 4 ) ;; 铁道部医学基金 (J99Z1 36)
【CateGory Index】: R114
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 6 Hits
1 PUYue-pu,YIN Li-hong,YUAN Hui(School of Public Health,Southeast University,Nanjing210009,China);Case-Control Study on Relationship between Hair Dye Use and Risk of Hematological Cancers[J];Journal of Labour Medicine;2003-06
2 ZHANG Juan,PU Yue-pu~*,YIN Li-hong,YUAN Hui,SONG Ya-hui (School of Public Health,Southeast University,Nanjing,210009,China);Relationship between Environmental Risk Factors, Genetic Polymorphisms of Metabolic Enzymes and Leukemia[J];Journal of Labour Medicine;2004-03
3 XU Yan-ying 1,Chen Yao Jin 2,WANG Xue-sheng 1,TONG Jian 1* (1.Sanitation Supervision Institute of Jin Chang District,Shouzou 215004; 2.School of Radiation Medicine and Public Health,Soochow University);Subchronic Toxicity of Oxidized Hair Dyes to Mice[J];Journal of Labour Medicine;2004-04
4 XU Yan-ying~1,TONG Jian~2 (1.Sanitation Supervision Institute of Jin Chang District,Shouzou 215004; 2.School of Radiation Medicine and Public Health,Soochow University);Advances in Toxicity Study on Oxidized Hair Dyes[J];Journal of Labour Medicine;2004-05
5 ZHANG Juan, PU Yue-pu Department of Occupational and Environmental Health,School of Public Health,Southeast University Nanjing 210009, China;Progress in Study on the Environmental Risk Factors and Susceptible Genes of Leukemia[J];Journal of Labour Medicine;2004-06
6 Chen Li,et al Department of Public Health,Luzhou Medical College;AFFECT OF HAIR DYE ON SKIN EPIDERMIS AND CORIUM ULTRASTRUCTURE OF GUINEA PIG[J];Journal of Luzhou Medical College;2008-04
【Citations】
Chinese Journal Full-text Database 2 Hits
1 LU Dong mei,PU Yue pu,YIN Li hong, et al Department of Environmental Health,Nanjing Railway Medical College,210009;Cytotoxicity of Oxidation Hair Dyes on Rat's Keratinocytes.[J];Journal of Environment and Health;2001-01
2 Huang Hua;Study of Percutaneous Absorption of Hair Dyes Through Rat Skin with the ~3H Labelled p-Phenylenediamine Tracing Technique[J];;1991-03
【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 LIU Qing, GUO Bao-lan, LI li, et al. Institute for Environmental Health and Related Product Safety, Chinese Center for Disease Control and Prevention, Beijing 100021, China;Study on Chromosome Aberration of CHO Cells Induced by Hair Dyes[J];Journal of Environment and Health;2006-03
2 HE Xiao-qiong,CHEN Yan-hong,WU Shuang-feng(Public Health Faculty of Kunming Medical College,Kunming 650031,China);Study of the Mutagenicity of 10 Hair Coloring Creams[J];Academic Journal of Kunming Medical College;2005-04
3 PUYue-pu,YIN Li-hong,YUAN Hui(School of Public Health,Southeast University,Nanjing210009,China);Case-Control Study on Relationship between Hair Dye Use and Risk of Hematological Cancers[J];Journal of Labour Medicine;2003-06
4 XU Yan-ying 1,Chen Yao Jin 2,WANG Xue-sheng 1,TONG Jian 1* (1.Sanitation Supervision Institute of Jin Chang District,Shouzou 215004; 2.School of Radiation Medicine and Public Health,Soochow University);Subchronic Toxicity of Oxidized Hair Dyes to Mice[J];Journal of Labour Medicine;2004-04
5 XU Yan-ying~1,TONG Jian~2 (1.Sanitation Supervision Institute of Jin Chang District,Shouzou 215004; 2.School of Radiation Medicine and Public Health,Soochow University);Advances in Toxicity Study on Oxidized Hair Dyes[J];Journal of Labour Medicine;2004-05
6 ZHOU Yong-gui,LI Zhen-guan(Shanghai Center for Disease Control and Prevention,Shanghai 200336,China);A Review of Mutagenicity,Carcinogenicity and Toxicokinetics of Hair Dyes[J];Journal of Environmental & Occupational Medicine;2008-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 ZHENG Wei-dong, XIN Pei-jun, YE Hong, YE Yu-wei, DONG Miao-zhu, XIAO Ping, LI Zhen-guan, ZHONG Wei-jian(Shanghai Center for Disease Prevention and Control, Shanghai 200336, China);STUDY ON THE MUTAGENIC EFFECTS OF AN OXIDATIVE HAIR DYE[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-01
2 FANG Si-xin, ZHANG Liu-xi,YAO Hui, LI Jia-tao (Hefei Center for Disease control and Prevention, Hefei, Anhui, 230061, China);Study of Influence Factors on Formaldehyde, Benzene series Concentrations in Newly Decorated Room[J];Anhui Journal of Preventive Medicine;2004-06
3 SONG Nan, TAN Wen, TANG Huai jing, et al.Cancer Institute, Chinese Academy of Medical Sciences and Beijing Union Medical College, Beijing 100021,P.R. China;Impact of cytochrome P450IA1 gene mutations on the risk of development of lung cancer in a Chinese population[J];CHINESE JOURNAL OF CANCER;1999-05
4 LIN Yue hao, LU Xi lin, SHAO Ming, et al Cancer Center,Sun Yat sen University of Medical Sciences, Guangzhou 510060,P R China;NAD(P)H:quinone oxidoreductase gene polymorphism and susceptibility of lung cancer[J];CHINESE JOURNAL OF CANCER;2000-05
5 Wu Xiao-Ming ,Zhou Yi-Kai,Ren Shu,Hao Qiao-Ling;Gene Polymorphism of Myeloperoxidase and Genetic Susceptibility to Lung Cancer[J];Chinese Journal of Cancer;2003-09
6 LU Yuan1,SUN Li-Rong1,PANG Xiu-Ying1,LU Zhen-Hua2,SUI Ai-Hua2,LI Xue-Rong1,SONG Ai-Qin1 1.Department of Pediatrics, Affiliated Hospital, Medical College, Qingdao University, Qingdao,Shandong,266003, P.R.China 2.Molecular Biology Lab, Affiliated Hospital, Medical College, Qingdao University, Qingdao,Shandong, 266003, P.R.China;Infection Status and Clinical Significance of Epstein-Barr Virus in Pediatric Leukemia——A Report of 35 Cases[J];Chinese Journal of Cancer;2007-01
7 WANG Yuzhen, GUO Shenbo, HAN Hua, et al\ Department of Pathophysiology, Qingdao University Medical College, Qingdao 266021;A STUDY OF ULTRAVIOLET B INDUCED APOPTOSIS OF HUMAN DERMAL FIBROBLASTS IN VITRO[J];Acta Acadimae Medicinae Qingdao;2002-04
8 YE Lin~1, XING Shen-yang~2, LU Yi~1, SUI Chun-sheng~1, WANG Chun-hua~1, ZHANG Li~△,LI Li~# (1. Department of Environment Hygiene, School of Public Health, Jilin University, Changchun 130021, China;2. Department of General Courses, School of Nursing,Jilin University,Changchun 130021,China);Effects of formaldehyde on lipid peroxidation and antioxidase in mouse brain tissues[J];Journal of Jilin University of (Medicine Edition);2005-04
9 WANG Hongwei, SHANG Lanqin, HAO Weidong △ (Department of Toxicology,Peking University School of Public Health, Beijing 100083,China);The induction of apoptosis and reactive oxygen species in human skin fibroblast by ultraviolet A[J];Journal of Beijing Medical University;2003-01
10 HUANG Mei WANG Xue-jun Yang Kai (East China University of Science and Technology,Shanghai 200237);Antioxidants of Chinese Materia Medica and in vitro Methods for Assessment of Antioxidant Activities[J];;2006-03
【Secondary References】
Chinese Journal Full-text Database 8 Hits
1 LI Xiao-jun SUN Shu-juan CHEN Wei FENG Cheng(School of Chemical Engeering,Hebei University of Technology,Tianjin 300130);A Study on the Synthesis of 5,6-Dihydroxyindole[J];Dyestuffs and Coloration;2007-01
2 DING Wen-qing, BAO Li, LI Zheng-zhi, et al. School of Public Health, Ningxia Medical College, Yinchuan, Ningxia 750004, China;The Risk Factors for Adult Leukemia: a Case-Control Study[J];Journal of Environment and Health;2006-03
3 ZUO Feng, DING Wen-qing, PAN Xiao-chuan, et al. Ningxia Medical College, Yinchuan, Ningxia 750004, China;Environmental Risk Factors for Child Leukemia in Ningxia:a Case-Control Study[J];Journal of Environment and Health;2007-09
4 Li Xiaojun, Jia Ruisheng, Chen Wei and Feng Cheng (School of Chemical Engeering , Heibei University of Technology , Tianjin 300130, China);SYNTHESIS OF 5,6-DIHYDROXYINDOLE[J];Speciality Petrochemicals;2007-02
5 ZHANG Juan,PU Yue-pu~*,YIN Li-hong,YUAN Hui,SONG Ya-hui (School of Public Health,Southeast University,Nanjing,210009,China);Relationship between Environmental Risk Factors, Genetic Polymorphisms of Metabolic Enzymes and Leukemia[J];Journal of Labour Medicine;2004-03
6 XU Yan-ying 1,Chen Yao Jin 2,WANG Xue-sheng 1,TONG Jian 1* (1.Sanitation Supervision Institute of Jin Chang District,Shouzou 215004; 2.School of Radiation Medicine and Public Health,Soochow University);Subchronic Toxicity of Oxidized Hair Dyes to Mice[J];Journal of Labour Medicine;2004-04
7 LI Li,MENG Fan-yi(Department ofHematology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China);Advances in Environment Risk Factor on Adult Leukemia[J];Journal of Environmental & Occupational Medicine;2006-04
8 Liu Jie,et al Department of Public Health,Luzhou Medical College;THE EFFECT OF HAIRDYES ON UTERINE TUBE OF FEMALE GUINEA PIGS[J];Journal of Luzhou Medical College;2007-05
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Huang Hua;Study of Percutaneous Absorption of Hair Dyes Through Rat Skin with the ~3H Labelled p-Phenylenediamine Tracing Technique[J];;1991-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved