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《Journal of Labour Medicine》 2003-03
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Dynamic Study on the Accumulative Levels of Benzene Hexachloride (BHC) and Dichloro-diphenyl-trichloroethane (DDT) in the Mothers' Milk in Shanghai

LI Yan hong 1,GUO Chang yi 1,WANG Guo quan 1,YANG Yu lin 1,ZHU Yi ping 1,XU Miao zhen 2,YUAN Hong 3,et al. (1.Department of Environmental Medicine,Shanghai Center for Disease Control and Prevention, Shanghai 200336; 2.Shanghai Chang Ning District Center for Disease Prevention and Control, Shanghai 200336; 3.Shanghai Jia Ding District Center for Disease Prevention and Control, Shanghai 201800)  
Objective] To study the accumulative levels of benzene hexachloride (BHC) and dichloro diphenyl trichloroethane (DDT) in the mothers milk in Shanghai from 1983 to 2002. The general evaluation of the effects of prohibition and restriction on use of BHC and DDT in China since 1983 were given in this paper. [Methods] In 1983,1986,1988 and 2002,the milk samples were respectively collected from women during lactation period in five districts of Shanghai and the contents of BHC and DDT in breast milk were determined according to Chinese standard method for biomonitoring. [Results] The median fat content of the mothers milk was about 2 450% in 2002. The median concentration of β BHC decreased from 22 6 μg/g in 1983 to 1 732 μg/g in 2002,and the levels of median BHC daily intake in the infants population was 6 540 μg/kg bw and less than ADI of WHO in 1989,but the rate over ADI is 18 30%. The median concentration of P,P DDE decreased from 13 900 μg/g in 1983 to 1 159 μg/g in 2002,and that of P,P DDT descended from 2 990 μg/g to 0 084 μg/g. The total median concentration of DDT dropped from 11 400 μg/g in 1988 to 1 287 μg/g in 2002. The levels of total DDT daily intake in the infants population was 4 014 μg/kg bw and less than ADI of WHO in 1989. [Conclusion] The accumulative levels of BHC and DDT had declined since 1983 BHC and DDT were prohibited. However,we should pay more attention to the further influence on the infants. And keep monitoring the contents of BHC and DDT in mothers milk.
【CateGory Index】: X503.1
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