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《Physical Testing and Chemical Analysis Partb Chemical Analgsis》 2001-03
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SIMULTANEOUS SPECTROPHOTOMETRIC DETERMINATION OF SULFAMETHOXAZOLE TABLETS BY ARTIFICIAL NEURAL NETWORKS

GENG Xin, LI Jinghui, GAO Lirang, CHEN Xingpan (Department of Applied Chemistry, Anshan Institute of Iron & Steel Technology, Anshan 114002, China) CHEN Guang (Tie xi Hospital Anshan)  
In this paper, a threelayer artificial Neural Networks (ANN) was applied to construct two models of ANN with Sigmoid function and hyperbolic tangent function as transformation function It is applied to the simultaneous determination of sulfamethoxazole and trimethoprim by UV spectrophotometry Error transfer functions of every model have all been improved δ k i=[f′(s)+0 1](T k i-Y k i) and δ k i =arcth ( T k i-Y k i) /2 instead of δ k i=f′(s)(T k i-Y k i ) which is proved to be as error transfer function, and make the derivative of transformation functions adjusted Because they do not approach towards zero, the paralysis can be avoided These methods can be applied to simultaneous determination of other mixtures
【CateGory Index】: O657.3
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