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《Physical Testing and Chemical Analysis(Part B:Chemical Analysis)》 2012-12
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High Performance Capillary Electrophoretic Determination of Huperzine A in Huperzine A Tablets

YU Yu-yan,ZOU Yan-hui,TENG Hai-ying,LIN Shu,ZHANG Hong-yan,LING Wei-jian(Pharmaceutical College,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China)  
A method for the separation and determination of huperzine A in its tablets by capillary electrophoresis was proposed.An acetate buffer solution of pH 4.6 was used as background electrolyte,and a moving voltage of 13 kV was applied.UV-detection at the wavelength of 310 nm was adopted.Linear relationship between values of peak area and mass concentration of huperzine A was kept in the range of 5.0-60 mg·L-1.The proposed method was applied to the determination of huperzine A in its tablets,giving values of recovery obtained by standard addition method in the range of 97.8%-98.7%,and RSD′s(n=5) in the range of 0.53%-0.85%.
【Fund】: 福建省科技厅重点项目(2011Y0035);; 福建省科技计划项目(2010Y2004)
【CateGory Index】: R286.0
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