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《Liaoning Journal of Traditional Chinese Medicine》 2005-10
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Effects of Anweitang Granule on the EGF and EGFR Expression in Gastric Mucosa of Experimental Rats

HUANG Gui-hua1,LIN Shou-ning1,WEI Wei2(1.Guangxi University of TCM,Nanning 530001,Guangxi,China;2.Digestion Department,Ruikang Affiliated Hospital of Guangxi University of TCM,Nanning 530001,Guangxi,China)  
Objective:To investigate the mechanism of Anweitang Granule in preventing and curing chronic gastric ulcer by making experimental rat-models of gastric ulcer induced by acetic acid.Methods: To observe the effects of Anweitang on the EGF and EGFR expression in gastric mucosa of experimental rats by means of immunohistologic staining;to analyze the images;and to process the statistic data.Results: Compared with the group of models,the EGF and EGFR expression in gastric mucosa in the group of Anweitang and Ranitidine are evidently enhanced(P0.05 or P0.001).The group of Anweitang(large dosage) is better than the group of Ranitidine(P0.01).Conclusion: Anweitang may enhance the EGF and EGFR expression in gastric mucosa and reinforce the mucosa's protection function and anti-relapse.
【CateGory Index】: R285.5;
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