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《Liaoning Journal of Traditional Chinese Medicine》 2007-10
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To Investigate Jiaohao Aetherolea Influence the Immune Function of Mouse

GUO Jian-lin1,HUANG Guo-fu1,E Xiao-zhe2,AN Chang-xin3(1.Cancer Medical Department of the Fifth Affiliated Hospital,Xinjiang Medical University,Urumuqi 830011,Xinjiang,China;2.Cancer Medical Department of the Affiliated Redevelopment Hospital,Beijing Medical University,Beijing 100038,China;3.Basic Department of Xinjiang Medical University,Urumuqi 830011,Xinjiang,China)  
Objective:To investigate Jiaohao aetherolea influence the immune hypofunction of mouse,which is induce by cyclophosphamide.Methods:sixty kunming species mouse are choosen random ten as normal control group(A group),the surplus are inoculated cyclophosphamide in belly cavity,50mg/kg.b.w,those are raised immune hypofunction models,then equaled random five parts :control model group(B group),healing groups by levamisole(C group),low dose(D group),midst dose(E group),high dose(F group) healing group by jiaohao aetherolea.Result:Eight immune indexes of C,D,E,F group are higher than B group,and partial immune indices of groups exceed that of C,D,E group.The weight of spleen and pleura increases obviously in C,D,E,F group by histopathologic examination,sebum thicken and achroacytosis.Conclusion:Jiaohao aetherolea can reinforce nonspecific immunity function and promote humoral immunity and cellular immunity function,so that cues that Jiaohao aetherolea may be a ideal immunomodulating drug.
【CateGory Index】: R285.5
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