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《Liaoning Journal of Traditional Chinese Medicine》 2008-12
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Effect of Hippocampus Cholinesterase for Alzheimer's Disease Model Treated by the Shallow Acupuncture to Regulate the Governor Meridian

FAN Yu-shan,CHEN Mang-hua,ZHAO Cai-jiao(The Acupuncture and Moxibustion Faculty of Guangxi Traditional Chinese Medicine University,Nanning 530001,Guangxi,China)  
Objective: To explore how to make Alzheimer's disease model and what is its mechanism,treated by shallow acupuncture to regulate the Governor.Methods: Rats were divided into four groups: the control group,model group,prevention group and treated group.The model group,prevention group and treated group were injected scopolamine hydrobromide injection 3mg/kg at abdomen,0.9%sodium chloride injection for the control group,once a day,successive 30 days.The prevention group was acupunctured from the first day,once a day,successive 30 days,and the treated group was treated after 30 days,method was the same with the prevention group.Then tested the rats' memory and activity by Morris water-maze.At the end of the experiment,taken out blood from inferior vena cava 5ml and hippocampus for every rat,saved in-75℃ refrigeratory for test.Results: Compared with the control group,the model group showed an significant difference on the levels of Hippocampus Cholinesterase and Maleic Dialdehyde of blood.It told us that the shallow acupuncture by regulating the Governor can treat Alzheimer's disease,and illustrate what is its mechanism.
【Fund】: 广西自然基金资助项目(桂科自0542098)
【CateGory Index】: R277.7
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