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《Liaoning Journal of Traditional Chinese Medicine》 2014-07
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Matrine Injection in Treatment of Non-Small Cell Lung Cancer and Its Impact on Quality of Life

SUN Yiwei;TANG Wenjing;School of Pharmacy,Nanjing Medical University;Department of Pharmacy,Jiangsu Cancer Hospital;  
Objective:To investigate matrine injections in the treatment of patients with advanced non-small cell lung cancer and impact on patients' quality of life.Methods:In our hospital,96 patients were treated advanced non-small cell lung cancer from June 2011 to July 2012,which were divided into observation group and the control group by 1:1.The control group received gemcitabine with cisplatin treatment and the observation group received matrine injection therapy on the based of control group.After two courses,we evaluated the efficacy and quality of life differences.Results:The control group' s total effective rate was 29.17% and control rate was 43.75% while the observation group's total effective rate was 66.67% and control rate was 85.42%.The observation group was significantly better than the control group(P 0.05).Toxicity of the observation group was 18.75% which was significantly lower than that of the control group which was 37.5% and the difference was statistically significant(P 0.05).Conclusion:Matrine injections can significantly improve the therapeutic effect of non-small cell lung cancer,and improve patients' quality of life,which has great value in the treatment of non-small cell lung cancer.
【CateGory Index】: R734.2
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