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《Journal of Diagnosis and Therapy on Dermato-venereology》 2015-02
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Correlation between Autoimmune Index and the Severity of Chronic Spontaneous Urticaria

LI Run-xiang;ZHANG Qian-wen;HUANG Zhen-ming;JIANG Na;LIU Qing;LIANG Bi-hua;CHEN Quan;LI Zhen-jie;ZHU Hui-lan;Guangzhou Institute of Dermatology;Guangzhou Medical University;  
Objective: To observe the relationship between autoimmune index and the severity of Chronic spontaneous urticaria. Methods: The serum levels of ASST,IgE,C3,C4,IgA,IgM,IgG,TPOAB and TGAB of 79 patients with Chronic spontaneous urticaria were detected. UAS7 method was used to evaluate the severity of 79 patients,and the correlation between the index above and degree were analyzed. Results: The positive rate of ASST was 54%. There were no correlation between the expression of ASST,IgE,C3,C4,IgA,IgM,IgG,TPOAB,TGAB and the UAS7 scores of chronic spontaneous urticaria( P 0. 05). Significant differences were found between the C3 concentrations of the mind degrees of urticaria severity and the moderate degrees( P 0. 05).Conclusion: To some extent,the expression of C3 could provide some reference to the severity of chronic spontaneous urticaria.
【Fund】: 广东省自然科学基金(编号:S2012020011077);; 广州市医药卫生科技一般引导项目(编号:20131A011128)
【CateGory Index】: R758.24
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 LI Run-xiang,ZHU Hui-lan,LIANG Bi-hua,GONG Ye-qing,XIAO Chang-qing,LI Jia-yan,LI Yang-qi,ZHANG Xi-bao( Guangzhou Institute of Dermatology and Venerology,Guangzhou 510095,China);Change of Peripheral Blood Lymphocyte Subpopulation and Levels of IL-15,IL-21 and IgE in Serum of Urticaria[J];The Chinese Journal of Dermatovenereology;2010-08
2 HE Ze-sheng1, AN Guo-zhi2, ZHAO Hai-chun3 (1. Department of Graduate Faculty, Hebei North University, Zhangjiakou 075000, China; 2. Department of Dermatology, the First Affiliated Hospital Hebei North University, Zhangjiakou 075000, China; 3. Department of Clinical Laboratory, the First Affiliated Hospital Hebei North University, Zhangjiakou 075000, China);Investigate Chronic Urticaria Patient’s Condition Correlating to C3, C4 of Peripheral Blood[J];The Chinese Journal of Dermatovenereology;2013-01
【Co-citations】
Chinese Journal Full-text Database 9 Hits
1 ZHANG Yong-ning;LIU Le;Department of Dermatology,Weinan Maternal and Health Hospital;Department of Dermatology,Shaanxi Provincial Institute for Endemic Disease Control;;Therapeutic efficacy of azelastine hydrochloride combined with BCG-PSN injection on chronic urticaria[J];Anhui Medical and Pharmaceutical Journal;2014-12
2 LIU Li-ling,MA Ji-chen,WANG Xian-ling,MA Yu-xin,WANG Li-sheng(Department of Dermatology,Bethune International Peace Hospital of PLA,Shijiazhuang 050082,China);Clinical Efficacy of Cetirizine Hydrochloride Combined with Catgut Embedding Therapy and Its Effect on the Sera Total IgE in Treatment of Chronic Urticaria[J];Clinical Misdiagnosis & Mistherapy;2012-10
3 WANG Min;Department of Dermatology & STD,Daye People's Hospital;;The clinical effect and mechanism of the combination therapy of BCG-PSN and antihistamine for chronic idiopathic urticaria[J];Chinese Journal of Aesthetic Medicine;2013-20
4 ;Yupingfeng Granule Combined with Cetirizine Hydrochloride in Treatment of Chronic Urticaria and Its Effect on Total Serum IgE[J];Hubei Journal of Traditional Chinese Medicine;2014-11
5 LI Run-xiang;FENG Cheng-en;LIANG BI-hua;TIAN Xin;ZHU Hui-lan;Guangzhou Institute of Dermatology and Venerology;Guangdong Pharmaceutical University;;A Mouse Model of Immunological Contact Urticaria by Anti-dinitrophenol IgE Combined with 2,4-Dinitrofluorobenzene[J];Journal of Diagnosis and Therapy on Dermato-venereology;2015-01
6 CHEN Nian;CHENG Qiong-hui;SUN Ren-shan;Department of Dermatology,the Third Affi liated Hospital of Third Military Medical University;;Layered treatmention urticaria[J];Journal of Practical Dermatology;2014-02
7 TU Hongwei;Xiantao No.1 People's Hospital;;Effect of autologous blood injection combined with antihistamines in the treatment of chronic urticaria patients with positive serum skin test[J];Journal of Clinical Medicine in Practice;2013-21
8 HUANG Tao-yuan;YANG Wen-lin;Department of Dermatology,the Second Affiliated Hospital of Guangzhou Medical University;;Acute-phase Response and Coagulation/Fibrinolysis in the Pathogenesis of Chronic Urticaria[J];The Chinese Journal of Dermatovenereology;2014-01
9 LI Zhao-yang;SUN Ren-shan;LI Jing;SONG Jun;WU Jin-jin;YANG Tao;TANG Hui;TANG Shu-qian;LI Feng;YANG Yong-qiang;Department of Dermatology,Daping Hospital/Institute of Surgery Research,the Third Military Medical University;;Detecting Histamine-Releasing Factor( HRF) and HRF-reactive IgE in the Sera of Patient with Chronic Urticaria[J];The Chinese Journal of Dermatovenereology;2014-05
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Che Jianli The 1st Affiliated Hospital of Suzhou University, Suzhou, Jiangsu 215006, China Chen Zhengqiu;The Effect of Acupuncture on Serum IgE Level in Patients with Chronic Urticaria[J];中医杂志(英文版);2006-03
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