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《Chinese Journal of Clinical and Experimental Patholog》 2001-02
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Primary lymphoma of bone:A clinicopathologic and immunohistochemical observation

Wang Zhihua, Wang Xiaoqiu, Fang Xuesong, Niu Junyang, Cheng Rongxuan (Department of Pathology, Anhui Provincial Hospital, Hefei 230001)  
Purposes To observe the clinicopathologic and immunohistochemical features of primary lymphoma of bone(PLB). Methods Eight cases of PLB were investigated by light microscopy and immunohistochemical staining. Results The mean age of eight cases of PLB was 51 years. Radiographs of all cases showed the lytic lesions or osteoporosises; All the cases were diffuse non Hodgkins lymphomas(NHL), including 4 large cell lymphomas (centroblastic, CB), 2 centrocytic(CC), one mixed cell (CB CC ) and one lymphoplasmacytic (LP); Immunohistochemical features revealed 6 cases of B cell, 2 T cell. Conclusions The peak incidence for PLB is in the 5th decade with the radiologic appearance of lytic lesions or osteoporosises. All tumors are the diffuse NHL, including mainly large cell lymphomas and immunophenotypic features of B cell lymphomas. Immunohistochemistry is helpful in the differential diagnosis of PLB.
【CateGory Index】: R738.1
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