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《Chinese Journal of Clinical Healthcare》 2006-04
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Effect of L-carnitine for treating congestive heart failure in the elderly

RUI Ming'an,SUN Yun,ZHU Jian,SHENG Jing(Department of Geriatric,The Ninth People's Hospital,Shanghai Jiaotong University,Shanghai 200011,China)  
Objective To observe the shortterm clinic effects of L-carnitine(LC) of treating congestive heart failure(CHF) in the elderly.Methods There were 37 elderly cases with CHF in LC group and 35 cases in control group.They all received basic treatment according to heart failure guideline.The patients in LC group additionly received LC injection 3g/d intravenous for 2wk.After 2wk,they consequently received oral LC 1g Bid for another 2wk.After 4wk,the patients' indexes including NYHA、EKG、UCG、MLWHF、Alb and PAlb before and after treatment in two groups were compared.Results ①After treatment,the patients' improvement of totle NYHA efficacy rates were no significant in two groups,but prominent efficacy rate in LC group was higher than that in control group.②After treatment,the indexes including SV、CO、EF、FS、VE/VA in LC group were significantly higher than those before treatment.③After treatment,the indexes including NST、ΣST were significantly higher than those before treatment and control group.④After treatment,the evaluation indexes of MLWHF in LC group was higher than that in before treatment,the indexes as Alb、PAlb in LC group were higher than those before treatment and in control group.Conclusion The combination treatment by LC is effective and safe for treating CHF in the elderly.
【CateGory Index】: R541.61
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【References】
Chinese Journal Full-text Database 3 Hits
1 WAN Jia-kui,SHUI Run-zhi,YU Lei(Hemopurication Centre of The People's Hospital of Huangshan,Huangshan,Anhui,245000);Relationship between the effect of erythropoietin and application of the L-carnitine in maintenance hemodialysis patients[J];Anhui Medical and Pharmaceutical Journal;2008-11
2 YU Tang-hong,HU Hong,LIU Jin-hong.Department of Nephrology,Jiangyin People′s Hospital,Affiliated to Southeast University,Jiangyin 214400,China;Effect of Levocarnitin on Cardiac Structures and Functions in Hemodialysis Patients[J];Chinese General Practice;2007-15
3 SHENG Yu,YU Jie,GUO Fei,HU Xin-ming(Department of Pediatrics,the Affiliated Hospital of Nantong University,Nantong 226001,Jiangsu Province,China);Curative Effects of L-Carnitine on Neonates with Myocardial Injury Caused by Asphyxia[J];Journal of Applied Clinical Pediatrics;2009-08
【Citations】
Chinese Journal Full-text Database 1 Hits
1 SUN Caixia, GAO Chunlin, XUE Yuliang, FENG Xuexin, ZHANG Yongqiang, GU ShuhuaDepartment of Anesthesiology, Second affiliated Hospital of Tianjin Medical University, Tianjin 300211, China;Effects of L-carnitine on Energy Metabolism of Myocardial Ischemia-Reperfusion Injury in Rats[J];Tianjing Medical Journal;2005-12
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 LIANG Jian-jun, WU Qiang, MIAO Li-ping, LU Ya-nan, ZHOU Mao Department of Anesthesia, the Second Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510260;The Application of L-carnitine in Elderly Patients Undergoing Emergency Operation[J];Lingnan Journal of Emergency Medicine;2006-03
2 ZHANG Yongqiang,GAO Chunlin,Lu Guoyi,LU Yuechun,DENG Naifeng Department of Anesthesiology,The 2nd Hospital of Tianjin Medical University,Tianjin 300211,China;Protective Effect of L-Carnitine in Cardioplegic Solution on Isolated Rat Hearts[J];Tianjin Medical Journal;2008-03
3 CHEN Chao-ting,CHEN Xiang-hua,HU Ping,et al.The Ninth People's Hospital Affiliated to Shanghai Jiaotong Medical University,Shanghai 200011,China;Efficacy and safety of L-carnitine in treatment of aged patients with chronic heart failure[J];Chinese Journal of Cardiovascular Review;2007-09
4 WANG Hong.The First Affiliated Hospital of Guangdong University of Pharmacy,Guangzhou,Guangdong Province 510080;Study on Curative Effect of L-carnitine on Chronic Cor Pulmonale[J];The Journal of Medical Theory and Practice;2006-07
5 Chen Dongmei,Shen Tao,Li Yujie,et al.Department of Cardiology,The Third People's Hospital of Bengbu,Bengbu 233000;Effects of L-carnitine on heart failure in the elderly patients with coronary heart disease[J];Modern Medicine Journal of China;2010-01
【Co-references】
Chinese Journal Full-text Database 9 Hits
1 WANG Cheng-fu,WANG Yi,YU Jia-fu,YANG Hai-yan,HE Xiao-xun(The Yicheng Hospital of Anqing,Anqing Anhui246003,China);To integrate L-carnitine with erythropoietin can improve maintenance hemodialysis patients'quality of life[J];Anhui Medical and Pharmaceutical Journal;2005-08
2 YANG Mu,DIAO Xiu-zhu,HUANG Ye-hua,REN Wei(Department of Nephrology,Anhui Provincial Hospital Hefei 230001,China);Effect of C-reactive protein on the response to erythropoietin in chronic hemodialysis patients[J];Anhui Medical and Pharmaceutical Journal;2006-08
3 YE Chao Yang, SHEN Lan Zhen, MEI Chang Lin, ZHANG Yi Xiang (Department of Nephrology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China);Effect of L -carnitine on anemia in hemodialysis patients treated with erythropoietin[J];Academic Journal of Second Military Medical University;2000-06
4 SUN Xiao,LI Lu,ZHAO Hong-li,et al.Department of Cardiology,the Shenzhou Hospital Affiliated to Shenyang Medical College,Shenyang 110002,China;Effect of L-carnitine on cardiac troponin T and C-reactive protein in patients with acute myocardial infarction[J];Chinese Journal of Practical Internal Medicine;2007-07
5 CHEN Yan-xia,WANG Jia-qin,XU Jian-wei;Changes of Myocardial Enzymes on Neonatal Asphyxia[J];Journal of Applied Clinical Pediatrics;2007-07
6 ZHAO Jing1,DONG Wen-bin1,WANG Ming-yong2,DENG Cun-liang2,CHEN Feng2,XU Kai-gui1(1.Department of Neonatology;2.Laboratory of Infection and Immunity,the Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China);Effect of Postasphyxial-Serum in Neonate on the Expressions of Bcl-2-Antagonist of Cell Death and Bcl-2-Associated X Protein in Renal Tubular Cells[J];Journal of Applied Clinical Pediatrics;2008-02
7 CHEN Yu-ling.(Department of Paediatrics,The First People's Hospital of Nanyang City,Nanyang 473000,China);THE THERAPEUTIC EFFECTS OF SHENMAI INJECTION ON HYPOXIC ISCHEMIC ENCEPHALOPATHY(HIE)COMBINED WITH MYOCARDIAL DAMAGE OF NEONATES[J];Modern Preventive Medicine;2007-20
8 ;Analysis of correlated factors of severe asphyxia in 71 newborns[J];Journal of Xinxiang Medical College;2004-02
9 SUN Qian-mei, WANG Zhi-gang. Department of Nephrology, ChaoyYang Hospital Affiliated to the Capital University of Medical Sciences, Beijing 100020, China;The study of erythropoiesis inhibitors in patients with uremia[J];Chinese Journal of Blood Purification;2006-06
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 XIAO Bei,KAN Ming,DING Qiong(Department of Nephrology,The Third Affiliated Hospital of Anhui Medical University,HeFei 230061,China);Clinical observation on the improvement of ascorbic acid on anemic and malnutrition of maintenance hemodialysis patients[J];Anhui Medical and Pharmaceutical Journal;2009-04
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 YIN Ren Fu 1, WANG Yong Mei 1, CHEN Jin Ming 1, WU Zong Gui 1, MEI Chang Lin 2, GU Shu Hua 3, ZHANG Chun 4 (1. Department of Cardiovasology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China; 2. Department of;Clinical study of L-carnitine improving heart function in patients with congestive heart failure[J];Academic Journal of Second Military Medical University;2001-02
2 ZHU Guang xu 1, XIE Yan 1, WANG Xiao hua 1, ZHOU Zhou 1, LOU Shu fen 2, YU Zheng ping 1 ( 1Department of Labor Hygiene, 2State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Combined Injury, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China);Effects of L-carnitine on energy production and CPT-Ⅱ mRNA expression in hypoxia/reoxygenation treated cultured neonatal rat myocardial cells[J];Acta Academiae Medicinae Militaris Tertiae;2004-03
3 Wang Furong,Yuan Zhihong,Xu Hongshi Division of Nephrology,Changzheng Hospital,The Second Military University,Shanghai 200003;THE ANTI ANEMIC EFFECTS OF COMBINED TREATMENT WITH L CARNITINE AND RECOMBINANT HUMAN ERYTHROPOETIN IN UREMIC PATIENTS[J];CHINESE JOURNAL OF NEPHROLOGY, DIALYSIS & TRANSPLANTATION;1999-02
4 JI Daxi*, XIE Honglamg, MEI Changlin,et al.* Institute of Nephrology, Jinling Hospital,Nanjing, 210002;Clinical trial of Lcarnitine in maintenance hemodialysis patients[J];CHINESE JOURNAL OF NEPHROLOGY;1999-03
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