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《Chinese Journal of Clinical Healthcare》 2006-04
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Effect of L-carnitine for treating congestive heart failure in the elderly

RUI Ming'an,SUN Yun,ZHU Jian,SHENG Jing(Department of Geriatric,The Ninth People's Hospital,Shanghai Jiaotong University,Shanghai 200011,China)  
Objective To observe the shortterm clinic effects of L-carnitine(LC) of treating congestive heart failure(CHF) in the elderly.Methods There were 37 elderly cases with CHF in LC group and 35 cases in control group.They all received basic treatment according to heart failure guideline.The patients in LC group additionly received LC injection 3g/d intravenous for 2wk.After 2wk,they consequently received oral LC 1g Bid for another 2wk.After 4wk,the patients' indexes including NYHA、EKG、UCG、MLWHF、Alb and PAlb before and after treatment in two groups were compared.Results ①After treatment,the patients' improvement of totle NYHA efficacy rates were no significant in two groups,but prominent efficacy rate in LC group was higher than that in control group.②After treatment,the indexes including SV、CO、EF、FS、VE/VA in LC group were significantly higher than those before treatment.③After treatment,the indexes including NST、ΣST were significantly higher than those before treatment and control group.④After treatment,the evaluation indexes of MLWHF in LC group was higher than that in before treatment,the indexes as Alb、PAlb in LC group were higher than those before treatment and in control group.Conclusion The combination treatment by LC is effective and safe for treating CHF in the elderly.
【CateGory Index】: R541.61
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