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《Journal of Liaoning University of Traditional Chinese Medicine》 2008-06
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Effect of Extract of Gynostemma on Activities of SOD and Capacity of Inhibiting OH.in Blood of Naturally Senile Mice

LIU Qing-qing,WU Jing-dong(Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China)  
Objective:To study the effect of the extract of Gynostemma on the activities of SOD and the capacity of inhibiting OH.in blood of the naturally senile mice and observe the organizational structure change of the naturally senile mice and presume the mechanism of the effect of Gynostemma on postoning the senescence.Methods: the kind of Kunming female mice aged in three-month formed a group as youth(A);the kind of Kunming female mice aged in twelve-month at random divides 3 group:old age blank group(B),old age masculine matched group(C),old age Gynostemma Pentaphyllum group(D).Did the intragastric administration with external use,and measured the activities of SOD and the capacity of inhibiting OH.by means of biochemical analytical method.Results: Comparing with youth group,the activities of SOD in blood reduces obviously among the others three old age groups(P0.01,P0.05,P0.05 respectively),and it is weakened by obviously to the capacity of inhibiting OH.(P0.01,P0.01,P0.05 respectively);Comparing with old age blank group,old age masculine matched group,and old age Gynostemma Pentaphyllum group can improve the activities of SOD(P0.05,P0.05 respectively) and the capacity of inhibiting OH.(P0.01,P0.01 respectively).Conclusion: Gynostemma can postone the senescence by increasing the activities of SOD and the capacity of inhibiting OH..
【CateGory Index】: R285.5
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