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《Journal of Liaoning University of Traditional Chinese Medicine》 2009-07
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Study on Protective Effects of Yougui Pill on Rats with Chronic Renal Failure

YU Hua-xin,WANG De-shan,SHAN De-hong (Liaoning University of Traditional Chinese Medicine, Shenyang 110032,Liaoning,China)  
Objective: To study the therapeutic effects of yougui pill on chronic renal failure(CRF) in rats. Methods:CRF model was induced by Adeine ig.The rats were randomized into normal group,model group,yougui pill group.After treatment, urine volume,Urine osmolality,renal function,renal pathologic changes,renal tissue ET-1 and Ang II were observed. Results:Compares with model group,the degree injury of renal function in yougui pill group was palliated significan,renal pathologic changes were palliated significan,renal tissue ET-1 and Ang II were both decreased significant.Conclusiion:Yougui pill has a therapeutic and preventive effect on CRF,and can prevent the generation and developnet of CRF,improve renal function.
【CateGory Index】: R285.5
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