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《Journal of Liaoning University of Traditional Chinese Medicine》 2017-03
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Research on Active Ingredients from Cinobufagin and Their Advances in Anti-tumor Mechanisms

JIA Xiaoqing;SUN Ping;Shandong University of Traditional Chinese Medicine;Affiliated Hospital of Shandong University of Traditional Chinese Medicine;  
Cinobufagin mainly contains bufogenin,indole alkaloids,polypeptide,cholesterin,the composition has many pharmacological activities,such as:anti-tumor,strong heart booster,analgesia effect. Anti-tumor mechanism mainly includes the inhibition of the growth of tumor cells,induce cell apoptosis and reversing multi-drug resistance,inhibiting tumor angiogenesis,enhance immunity,antiinflammation and so on. This paper will rewiew the latest progress on its active ingredients and anti-umor mechanisms,in order to provide the reasonable and reliable basis for clinical application and preparation of new dosage forms.
【CateGory Index】: R285
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