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《Acta Academiae Medicinae Weifang》 2006-01
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The Clinical Value of ~(99)Tc~m-DTPA Renal Dynamic Imaging in Nephrotic Syndrome

XIE Hai~1,LI Xian-jun~1,YU Ming-ming~1,LI Xu-bin~1,WANG Yan-juan~1,LI Xiang-ling~1,SUN Jian-mei~2(~1Department of Nuclear Medicine,the Affiliated Hospital of Weifang Medical College,Weifang 261031,China;~2The Second People's Hospital of Weifang)  
Objective To analyse the clinical value of ~(99)Tc~m-DTPA renal dynamic imaging in nephrotic syndrome(NS).Methods Twenty normal persons and thirty-eight patients with nephrotic syndrome were examined by ~(99)Tc~m-DTPA renal dynamic imaging.In each case,glomerular filtration rate(GFR),the time reaching highest aggregation(T_p),the time of half excretion(T_(1/2)),the excretion rate at 20min(R_(20)) and the imaging character of the renal cortex were all observed.For all the items,the diagnosis value index including Sensitivity,Specificity,chief Accordance and Kappa was calculated.Simultaneously,the urine protein and plasma albumin result was noted for every cases.The diagnosis results of ~(99)Tc~m-DTPA renal dynamic imaging were made respectively by two doctors without knowning the urine protein and plasma albumin result of the case.Results The sensitivity of ~(99)Tc~m-DTPA renal dynamic imaging in diagnosing NS(82.25%) was higher than that of urine protein and plasma albumin(63.2%,P0.05).All the items of ~(99)Tc~m-DTPA renal dynamic imaging had respective value in diagnosis,but their single value was much lower than that of the diagnosis results made by doctors through general analysis.Conclusion ~(99)Tc~m-DTPA renal dynamic imaging is a very efficient way to evaluate renal function.It is very important to generally analyse all the items of ~(99)Tc~m-DTPA renal dynamic imaging in order to diagnose NS at early stage.
【CateGory Index】: R817.4
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