Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Mudanjiang Medical College》 2008-03
Add to Favorite Get Latest Update


Niu Yan etal (Tianli Medicine Limited Company of Mudanjaing,Mudanjaing Heilongjiang 157000)  
Objective:To observe the effect of Total Astragalosides (TA) on proliferation of human lung cancer cell line A549.Method:Using cell culture,MTT assay,DNA agarose gel electrophoresis and flow cytometry to observe the effect of TA on proliferation of human lung cancer cell line A549.Result:TA suppressed the growth of A549 cells markedly and induced apoptosis in a dose and time dependent manner.The treated cells exhibited obvious apoptosis.The characteristic ladder-like DNA fragment appeared in the cells.Conclusions:TA can inhibit the proliferation of human lung cancer cell A549 in vitro.The effect is dose and time dependency.It can also induced apoptosis that may be related to arresting cell cycle at G1 phase by TA.
【CateGory Index】: R734.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 7 Hits
1 Liu Tangwei, Wu Weifeng, Feng Zhenbo, et al.(Department of Cardiology,the First Affiliated Hospital, Guangxi Medical University, Nanning 530021 China);EFFECTS ON APOPTOSIS AND Bcl-2/Bax GENE TRANSCRIPTION IN THE DEVELOP-MENT VIRUS MYOCARDITIS IN MICE TREATED WITH ASTRAGALUS[J];Journal of Guangxi Medical University;2003-06
2 Chen LX, Zhu HY, Zhu LQ, Xie LD, Lin Q, Zhang Y 1Department of Cardiovascular Medicine, Beijing Royal Integrative Medicine Hospital, Beijing 102209, China; 2Key Laboratory of Chinese Internal Medicine of Ministry of Education, Beijing University of Chinese Medicine, Beijing 100700, China; 3Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China; 4Beijing University of Chinese Medicine, Beijing 100029, China;Effects of astragalus polysaccharides on the proliferation of human cardiac microvascular endothelial cells adherent to polymorphonuclear neutrophils after reperfusion injury[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-27
3 YANG Yan, CHEN Min Zhu (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032);Effects of total astragalosides on hepatoma cells apoptosis and wtp53 expression[J];Chinese Pharmacological Bulletin;2001-04
4 XU Du Juan, WU Qiang, YANG Yan, CHEN Ming Zhu (Institute of Clinical Pharmacology,Anhui Medical University,Hefei 230032);Antitumor activity of AST and its mechanism of action[J];Chinese Pharmacological Bulletin;2003-07
5 CHU Zhonghua, CHEN Tao, OU Qingjia, et al. Department of General Surgery, Sun Yet-Sen Memorial Hospital, Sun Yet-Sen University of Medical Sciences, Guangzhou 510120, P. R. China;Application of in vitro ATP-TCA and FCM in chemotherapy of primary liver cancer[J];Chinese Journal of Hepatobiliary Surgery;2002-12
6 [HJ*2]Qin Xuhua~ 1 , Jin Shenrui ~ 2 ,Qu Yan~ 3 (~ 1 College of Pharmacy,Chengdu University of TCM,Chengdu 610075; ~ 2 College of Preclinical Medicine, Chengdu University of TCM, Chengdu 610075);Antitumous effects of Astragalus polysaccharide, Astragaloside IV and Astragalus mongholicus injection on diverse human malignant tumor cell strains(SMMC7721,PC-3,HL-60)[J];Pharmacology and Clinics of Chinese Materia Medica;2006-06
7 CAI Xiao-yan, XU Yan-li, LIN Xiao-jun, et al Department of Rheumatology, The First Municipal People's Hospital of Guangzhou, Guangzhou (510180);Effects of Radix Astragali Injection on Apoptosis of Lymphocytes and Immune Function in Patients with Systemic Lupus Erythematosus[J];Chinese Journal of Integrated Traditional and Western Medicine;2006-05
Chinese Journal Full-text Database 10 Hits
1 LI Jian et al(College of Enviroment and Chemical Engineering,Yanshan University,Qinhuangdao,Hebei 610400);Study on Antitumor Activity and Immunomodulating Effect of Polysaccharides Isolated from Solanum nigrum Linne[J];Journal of Anhui Agricultural Sciences;2008-33
2 XIA Quan1,LIU Gang2,GE Chao-liang1,XU Du-juan1(1.Department of Pharmacy,The First Affiliated Hospital of Anhui Medical University,Hefei 230022;2.School of Pharmacy,Anhui Medical University,Hefei 230032);Removal of proteins from crude astragalus polysaccharides by sevag method[J];Anhui Medical and Pharmaceutical Journal;2007-12
3 XU Du-juan,CHEN Min-zhu (The Department of Pharmacy,the First Affiliated Hospital of Anhui Medical University,Anhui Hefei 230022, China);Protection of Total Astragalus Extract Against Chemotherapy-induced Leukopenia and Immunosuppression in Tumor Bearing Mice[J];Journal of Anhui Traditional Chinese Medical College;2006-03
4 JIN Guang-ming,ZHAO Gui-fang,CHEN Juan(Animal Science College,Anhui Science and Technology University;Anhui Key Laboratory of Poultry Infectious Disease Prevention and control,Fengyang 233100,China);Effect of Astragalus Polysaccharide on Chicks Performance[J];Journal of Anhui Science and Technology University;2008-04
5 WANG Chun,GAO Xue-min,ZHANG Jian-jun(Beijing University of Chinese Medicine,Beijing100029,China);Selecting Chinese materia medica to treat Pa disease depending on differentiation of syndrome and differentiation of disease[J];China Journal of Traditional Chinese Medicine and Pharmacy;2008-07
6 LUO Xue-ya, GAO Wei, LUN Yong-zhi, JIN Li-xin, ZHAO Lian-hua, CAO Li-li(Medical College of Dalian University, Dalian 116622, China);Studies on acute toxicity of Astragalus composition F_3 new preparation[J];Journal of Dalian University;2002-06
7 LUN Yong-zhi, LI Ming-hui, LUO Xue-ya, LIU.Ya-li, ZHAO Lian-hua, CAO Li-li (Medical College of Dalian University, Dalian 116622, China);Experimental study on antitumor with astragalus composition F_3 new preparation[J];Journal of Dalian University;2003-04
8 LUO Qing, SONG Guan-bin, QIN Jian, SHEN Xiao-dong (Key Laboratory for Biomechanics and Tissue Engineering Under the State Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400030, China);Progress of Research on Hepatocellular Carcinoma Cells Apoptosis Induced by Chinese Traditional Medicine[J];Journal of Chongqing University(Natural Science Edition);2005-07
9 WANG Chang-kang~1,LIU Hao~1,WU Zhen-mi~1,LI Wen-sheng~2,GUAN Lan-gui~2,SHAO Liang-ping~1(1.College of Animal Science,Fujian Agriculture and Foresty University,Fuzhou, Fujian 350002,China;2.Fujian Sunner Development CO,LTD,Guangze,Fujian 354100,China);Effects of basic diets with mucaosu,enramycin and lincomycin on development of immune organs and production performance in broiler chickens[J];;2005-04
10 WANG Chang-kang,LIU Hao,SHAO Liang-ping(1.College of Animal Science,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China);Effects of Mucaosu on the laying performances and serum parameters in laying hens[J];Fujian Journal of Agricultural Sciences;2006-03
China Proceedings of conference Full-text Database 1 Hits
1 Zhong-qi Wang Zhen-ye Xu Hai-bin Deng Wei-dong Zhou Ming Zhang Ji Wu Li-fang Wang Bing Bai Department of Oncology,Longhua Hospital Affiliated to Shanghai University of TCM TCM Institute of Oncology,Shanghai University of TCM;Feiyanning's Effect on Restraining Growth,Metastasis and Angiogenesis of Lewis Tumor Loaded in C57 Mice[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Zhong Guogan, Jiang Yan, Wei Yongdi, An Zhanyuan,Sun Xiaoxia,Li Yunyi (Depart of Physiology, Central Laboratory of Physiology, Depart of Organic Chemistry);Positive inotropic action of astragalus membranaceus atponins on lsolated Working Heart[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1994-05
2 ZHAO Lian-hua, JING Li-xin, CHEN Yong-mei, CAO Li-li, LUO Xue-ya, YUE Ming, MA Yan-jie, GAO Le (The Medical College of Dalian University, Dalian 116622, China);Study on inhibitory effect of F3 new preparation from Astragalus membramaceus on the cell of human stomach cancer[J];Journal of Dalian University;2003-02
3 ZHANG Hong-ying,SUN Yan-qiu,L Shen [WT5BX](Department of Pathology,Dalian Medical University,Dalian 116027,China) [WT5HZ];Effect of TPN being added Huang Qi upon the immune function of patients with stomach cancer in perinatal surgery[J];JOURNAL OF DALIAN MEDICAL UNIVERSITY;2000-02
4 SUN Yan, YANG Jie Department of Pharmaceutics, General Hospita l of PLA, Beijing 100853, China;Experimental study of the effect of Astragalus membranaceus against herpes simplex virus type1[J];Journal of First Military Medical University;2004-01
5 ZhangDongqing, Wang Shujun, Ma Anlun, Zhou Guangyan, Qiu Chaolin, Gu Yueying, Chen Shunle. Shanghai Institute of Immunology, 200025 .;CONTRASUPPRESSOR AND Y5-TCR POSITIVE T CELL IN SLE[J];;1997-04
6 WANG Xiaofei,JIANG Li,ZHAO Lijuan,et al.China Medical University,Shenyang 110001;Lymphocyte apoptosis in the peripheral blood of active systemic lupus erythematosus patients[J];CHINESE JOURNAL OF RHEUMATOLOGY;1999-04
7 LI Zhijun , WEI Lianbo, HE Feng, et alNan Fang hospital, Guangzhou (510515);Effect of Astragalus polysacchride on the Mesangial proliferative glomerulonephritis in rat's[J];Chinese Journal of Integrated Traditional and Western Nephrology;2000-04
8 Shi Renbing , Liang Xiaoqiu , Liang Jichun ,et al. (Beijing University of Traditional Chinese Medicine, Beijing 100029) T6;Effects of Astragalus S4 On the Cellular Immune Function of Tumorigenic Mice in Chemotherapy and the Inhibitory Action[J];JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE;1999-02
9 Liu Hui,Li Jinrong,Hu Chuanzhen.College of stomatology of Hubei medical University,Wuhan(430079);Study of the Immunoenhancement and Anti-cancer Effect of Astragalus Membranaceus on Human Squamous Cell carcinoma Cell Line GNM[J];STOMATOLOGY;1999-02
10 Jiang Qinglin; et al;Effects of Asl on insulin and C-peptide[J];HEILONGJIANG MEDICINE AND PHARMACY;1999-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved