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《药用植物研究(英文版)》 2010-09
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Effects of Polyphenols from Toona sinensis(A.Juss.) Roem.Seeds on the Cardiogram and Hemodynamics MIR Rats

LI Hong-yue,CHEN Chao* Medical College,China Three Gorges University,Yichang,Hubei 443002,China  
[Objective]To investigate the effects of total polyphenols extracted from Toona sinensis(A.Juss.) Roem.seeds on the cardiogram and hemodynamics of myocardial ischemia reperfusion(MIR) rats.[Method] Fifty SD rats were divided into 5 groups(sham operation group,model group,XD group,XZ group and XG group) randomly.Myocardial ischemia reperfusion injury model was induced by ligaturing the left anterior descending(LAD) of coronary artery for 30 min,and the changes of electrocardiogram before ligation,30 min after ligation,and 30,60 and 90 min after reperfusion were detected and recorded.In the end,LVSP,LVDEP,±dp/dtmax and HR were detected.[Result] Compared with the rats in model group,the height of J point of myocardial ischemia reperfusion rat treated with total polyphenols extracted from Toona sinensis(A.Juss.) Roem.seeds descended,and the injury level of LVSP,LVDEP,±dp/dtmax and HR relieved.[Conclusion] Total polyphenols extracted from Toona sinensis(A.Juss.) Roem.seeds played a protective role in myocardial ischemia reperfusion induced injury.
【CateGory Index】: S567.19
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