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《Journal of Mianyang Normal University》 2012-02
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On Effects of Flavonoids from Pholiota Adiposa on Free Radical Metabolic Level of Rat Skeletal Muscle Tissue After Excessive Exercise and its Mechanism

WU He-qun,WANG Yong(Department of Physical Education,Sanming College,Sanming,Fujian 365004)  
The research of over-training on skeletal muscle tissue and blood levels of free radical metabolism and major metabolic enzyme activity is to reveal the effects of oxidative defense of flavonoids from pholiota adiposa on rat skeletal muscle after excessive exercise,and explore the possibility of mechanism.The results show,comparing the excessive training group with the less training one,SOD、GSH-PX、T-AOC in rat skeletal muscle decrease significantly,while MDA、CK、NOS significantly increase,indicating that the level of skeletal muscle tissue's lipid peroxidation rises,and the damage of muscle cells is obvious,but the skeletal muscle tissue in the intervention group has a good improvement.That is to say,flavonoids from pholiota adiposa can improve the level of free radical metabolism in rats,enhancing the activity of anti-oxidase,being in favor of protecting the integrity of the Skeletal muscle tissue structure and its function,ans it can be further studied and developed as the fungus resource for anti-oxidant and microecologics.
【Fund】: 福建省教育厅A类自然科学研究项目(JA10265);; 三明学院海西建设科技开发与文化建设专项(HX201008/Z)
【CateGory Index】: R87
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