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Experimental study of Nao Gong Fu De in treatmint of Parkinson's disease

Lv Shengqing,Zhang Kecheng,Cai Wenqin,He Jiaquan,Liu Shiyong Department of Neurosurgery,Xinqiao Hospital,Third Military Medical College,Chongqing 400037 * Department of Histology and Embryology,Third Military Medical College,Chongqing 400038  
Objective:To investigate the therapeutic effect of Nao Gong Fu De (NGFD)in Parkinson's disease (PD). Methods:The Parkinson's disease models were creaed by unilateral substantia nigra injection of neurotoxin 6-hydroxydopamine (6-OHDA) using stereotactic method,which can destroy selectively the catecholaminergic neurons and their endings.Nao Gong Fu De were injected into the stomachs of the models for 3 weeks,and then,the rotational behavior of PD rats was observed at the different time.The rats were killed three months later,and the quantities of dopamine (DA) in the striatums were evalusted by high performance liquid chromatography with electrochemical detection (HPLC-EC).Results:The rotational behavior of PD rats in treatment group reduced significantly after 2 weeks,1 month、2、3 months.The quantities of DA in the striatums increased much more than the group without NGFD.Conclusions:Nao Gong Fu De is an effective Chinese medicine for Parkinson's disease.
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Chinese Journal Full-text Database 4 Hits
1 Zhou Mingfu;Zhang Hua;Wu Jinliang;Guo Zhangsheng;LinLing;Tang Shanjun;Zhou Xiangting(Department of Anatomy,Henan Medical University,Zhengzhou 450052);Establishment of animal model for Parkinson's disease[J];JOURNA OF HENAN MEDICAL UNIVERSITY;1994-04
3 WangAimin; CaoYinglin; WangYukun; ZhaoRunzhou and LiuChongming(Shenyang Pharmaceutical University 110015);Effects of Chinese Ginseng Root andStem-leaf Saponins on Learning , Memory and BiogenicMonoamines of Brain in Rats[J];CHINA JOURNAL OF CHINESE MATERIA MEDICA;1995-08
4 Yang Hui , ZhangKe-cheng, Cai Wen-qin Department of Neuro-surgery, he second affiliated hopital of thethird military medical university 630037.;The changes of the levels of monoaminer-gic neurotransmitters and the densities ofdopamine D_2 receptors following intracerebralimplantation of AM grafts[J];CHINESE JOURNAL OF EXPERIMENTAL SURGERY;1995-04
Chinese Journal Full-text Database 10 Hits
1 YANG Guo yu, FENG Zheng zhi, HUANG FU En,MIAO Dan ming, WANG Jia tong(Educational Center of Mental Health, Third Military Medical University, Chongqing 400038, China);Effects of ginsenosides on rats' serotonin of raphe ceruleus during sleep deprivation[J];Acta Academiae Medicine Militaris Tertiae;2002-02
2 YU Xiao qiang 1, RUAN Huai zhen 1, CAI Wen qin 1, FAN Xiao tang 1, YAO Zhong xiang 2, YANG Hui 3 ( 1Department of Neurobiology, 2Department of Histology and Embryology, College of Medicine, 3Department of Neurosurgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400038, China);Striatal extracts of PD rats induce differentiation of mesencephalic neural stem cells into dopaminergic neurons[J];Acta Academiae Medicinae Militaris Tertiae;2004-01
3 WU Qiang 1, LI Yun-peng 1, YANG He-ping 2, LE Wei-dong 3, DONG Zhao-jun 1 ( 1Department of Military Toxicology, College of Preventive Medicine, 2Department of Respiratory Diseases, Southwest Hospital, Third Military Medical University, Chongqing 400038, China; 3Department of Neurology, Baylor College of Medicine, TX77030, USA);Effects of long-term rotenone intoxication on the monoamine neurotransmitters, NO, and NOS in rat striatum[J];Acta Academiae Medicinae Militaris Tertiae;2004-22
4 Tian Jinbin ,Fang Ming,Liu Xuesong,Xu Wei and Han Jisheng (Neuroscience Research Center,Beijing Medical University,Beijing 100083);High Performance Liquid Chromatography with Electrochemical Detector for the Determination of Monoamines and Their Metabolites in the Spinal Perfusate of Rat[J];ANALYTICAL LABORATORY;1998-01
5 SU Ping, LI Yan-hua, ZHENG Min, et al. Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;Establishment of an improved rat model of Parkinson's disease[J];Guangdong Medical Journal;2006-07
6 ZHOU Hou-guang, BAO Yuan-cheng, LU Jian-ming. Department of Neurology,Affiliated Changshu Hospital, edical College of Yangzhou University, Changshu, Jiangshu 215500, China;Establishment of an improved rat model of Parkinson's disease[J];Foreign Medical Sciences Section On Neurology & Neurosurgery;2005-04
7 Zhang Xiaolei, et al Guizhou Geriatrics Institute;Assay Procedures for the Determination of Monoamines in Rat's Brain by Means of Reversed-Phase Ion-Pair Chromatography with Electrochemical Detection[J];Journl of Guiyang Medical College;1992-02
8 YIN Feng,TIAN Zeng-min,ZHAO Quan-jun,WANG Ya-ming,YU Xue,LIU Shuang(Department of Neurosurgery,Naval General Hospital,Beijing 100037,China);Experimental Study on Establishment of Rats Model of Parkinson Disease by 6-OHDA Injection[J];Journal of Naval General Hospital;2007-02
9 GAO Shi-Yong 1,NI Xiao-hu 1,YU Lei 1,LI Min 1,LI Ye 2 (1 Department of Pharmaceutical Engineering ,Harbin University of Commerce,Harbin 150076,China; 2.Department of Physcial Culture,Harbin University of Commerce,Harbin 150076,China);Study on antidepressant-like effect of ginseng stems and leaves saponins(GSLS)and ginseng roofs sapmins(GRS)[J];Journal of Heilongjiang Commercial College (Natural Sciences Edition);2002-02
10 Hu LixianDepartment of Nuclear Medicine, The First Affiliated Hospital, Hunan Medical UniversityLiu AipingInstitute of Combined Traditional Chinese and Western Medicine, Hunan Medical University;PLASMA EPINEPHRINE AND NOREPINEPHRINE IN THYROID DISORDERS[J];;1990-04
Chinese Journal Full-text Database 10 Hits
1 Gu Guixiong;Zhu Lingli;Jiang Ying Children's Hospital, Suzhou Medical College Suzhou 215003 China;THE RELATION BETWEEN TAURINE AND GROWTH[J];;1993-04
2 Wang Lei, Yue Wang, Zhao Yongjuan, et al Department of Pharmacology, Qingdao Medical College, Qingdao 266021;INHIBITORY EFFECT OF TAURINE ON THE DEVELOPMENT OF AMYGDALA KINDLING IN RATS[J];;1998-01
3 $$$$;Amulti-function box for conditioned reflex training of passive avoidance behavior of rats[J];ACTA ACADEMIAE MEDICINAE MILITARIS TERTIAE;1994-05
4 $$$$;Estimation of cytosolic free calcium within synaptosomes with fluorescent indicator Fura-2[J];ACTA ACADEMIAE MEDICINAE MILITARIS TERTIAE;1995-04
5 Liu Hua, Pu Haiping, Yao Qian. The 401st Naval Hospital,Qingdao 266071;A Study of Protective Effect of Taurine on Brain Cells with Ischemic Reperfusion Damage in Rats.[J];CHINESE JOURNAL OF CHILD HEAITH CARE;1999-03
6 Tan leyi,Zhang Chaohua,Xue Changhu,Lin Hong,Li Zhaojie (Food Engineering Department of Qingdao Ocean University ,Qingdao 266003);THE PRESENT STUDY ON THE CELL-PROTECTIVE EFFECT OF TAURINE[J];CHINESE JOURNAL OF MARINE DRUGS;2000-04
7 Zhang Yi Lou Ailin(Oept. of Physiology, Institute of Clinical Medical Sciences, China-Japan Friend hip Hospital);Effect of Ginsenosides on Efficiency of Synaptic Transmission in Hippocampal Dentate Gyrus and Behavioral Memory in Rat[J];Basic Medical Sciences and Clinics;1993-05
8 Wang Jixian Yao xinghai Wang Lizhi Li Yan Su jingyi Tang Chaoshu(Institute of Cardiovascular Basic Reseach,Beijing Medical University,Beijing 100083);Experimental Study of Taurine Protective Effect on Hypoxia/ Reoxygenation in Isolated Rat Spinal Cord[J];BASIC MEDICAL SCIENCES AND CLINICS;1998-03
9 Chen Yuncai;Yao Zhibin;Chen Yici;Kuang Guobi(Brain Research Unit,Department of Anatomy,Sun Yat-sen University of Medical Sciences,Guangzhou);EFFECTS OF PHYSICAL EXERCISE ON SYNAPTOPHYSIN IN CEREBELLAR CORTEX AND SPINAL CORDIN MICE[J];ACTA ANATOMICA SINICA;1994-03
10 Sun Guiju,Pu Yuepu,Teng Man,Tan Weijun,Jiang Zhaokun (Nanjing Railway Mendical College,Nanjing,210009) Huang Jie,Zhou Zixin (Nanjing Sanitation and Antiepidemic Station,Nanjing,210037) Wei Ping (Nanjing Hongqi Milk Product Factory,Nanjing,210040);Protective Effects of Taurine Against the Inhibition of the Rat Embryo Midbrain Neural cells Differentiation by Vitamin A[J];JOURNALOF NANJING RAILWAY MEDICAL COLLEGE;1997-03
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