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《Journal of Nanjing Forestry University(Natural Sciences Edition)》 2008-02
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Antifungal activities and synergetic tests of matrine and oxymatrine to some tree pathogens

YANG Xue-yun1,2,ZHAO Bo-guang1,JU Yun-wei1(1.College of Forest Resources and Environment Nanjing Forestry University,Nanjing 210037,China;2.College of Sciences Nanjing University of Technology,Nanjing 210009,China;)  
The anti-fungi activities of matrine and oxymatrine on five forest pathogenic fungi,i.e.,Fusarium oxysporum,Valsa pini,Cladosporium oxysporum,Sphaeropsis sapinea,Marssonina brunnea were examined.The results showed that matine and oxymatrine had strong inhibitory activities on the conidium germination of the fungi.The EC50 values of matrine on M.brunnea,C.oxysporum were 123 μg/mL and 272 μg/mL,respectively.The EC50 value of oxymatrine on F.oxysporum,were 26 μg/mL,which was better than that of 75% chlorthaloni(91 μg/mL) and 70% thiophanate methyl(283 μg/mL).Matrine and oxymatrine also significantly inhibited the hyphal growth of the fungi.The EC50 value of matrine on S.sapinea,was 428 μg/mL and the EC50 value of oxymatrine on V.pini,was 323 μg/mL.In the synergetic tests the EC50 values of the mixtures of thiophanate methyl(or chlorthaloni) and matrine(or oxymatrine) were less than 34 μg/mL while their co-toxicity coefficients were significantly higher than 100.It was suggested that the mixture would have potential utilization in controlling certain forest pathogens.
【Fund】: 国家自然科学基金资助项目(30170776)
【CateGory Index】: S767.1
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