Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Acta Academiae Medicinae Nanjing》 2004-01
Add to Favorite Get Latest Update

NF-κB Expression in LPS Induced Acute Lung Injury in Mice

ZHU Zi-lu,XIONG Jun,XU Hua,LU Shan-hua,SUN Ai-min(Department of Biochemisty and Molecular Biology,NJMU,Nanjing 210029,China)  
Objective:To investigate the function of nuclear factor-êB(N F- êB) in acute lung injury(ALI),the dynamic change of NF-êB in lung of ALI was detected. Methods:Twenty five male mice were divided into five groups at random . There were normal control group and four acute lung injury groups at different time point.The lipopolysaccharide(LPS)was admistrated by intraperitoneal inje ction. Expression of NF-êB was detected by the methods of Western-blot and im munohistochemistry. Results:Expression of NF-êB began to increase after injec ting LPS in the first hour,arrived the peak in the third hour and then decreased . Conclusion:NF-êB may be a key medium in ALI.
【CateGory Index】: R563.8
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 YANG Ai-dong,LI Wen-wen,WANG Dong-ying,et al Shanghai University of Traditional Chinese Medicine(Shanghai 201203);Effects of Hujin Decoction on Expression of NF-κ B mRNA in the Rats with Acute Lung Injury[J];Journal of Emergency in Traditional Chinese Medicine;2009-10
Chinese Journal Full-text Database 1 Hits
1 ZHU Zi-lu, WANG Ruo-ning, SHEN Qi, LI Chong-yong, SUN Ai-min, CHEN Bing-ying (Department of Biochemistry and Molecular Biology, NJMU, Nanjing 210029, China);Cloning of IκB-α Gene and Construction of Its Eukaryotic Expression Vector[J];Acta Academiae Medicinae Nanjing;2002-02
Chinese Journal Full-text Database 2 Hits
1 ZHU Zi-lu, CHENG Zhi-xiang, XIONG Jun, CHEN Bing-ying Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing 210029, China;Construction of recombinant ΔN IκBα adenovirus and its suppression of NF-κB activity in A549 cells[J];Journal of Cellular and Molecular Immunology;2005-02
2 ZHOU Lin-fu1,ZHU Yi1,ZHU Zi-lu2,YIN Kai-sheng1(1Department of Respiratory Medicine,The First Affiliated Hospital,2 Department of Biochemistry and Molecular Biology,Nanjing Medical University,Nanjing 210029,China);Construction and identification of recombinant adenovirus vector carrying a N-terminal phosphorylation sites-deleted human IκBα mutant gene[J];Chinese Journal of Pathophysiology;2006-09
Chinese Journal Full-text Database 10 Hits
1 Sheng Zhiyong, Yao Yongming, Lin Hongyuan. The 304 Hospital of PLA, Beijing 100037;THE EVOLUTION AND PROGRESS IN OUR UNDERSTANDING OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME AND MULTIPLE ORGAN DYSFUNCTION SYNDROME[J];Medical Journal of Chinese People's Liberation Army;2002-02
2 Guo Zhenghui,Hong Xin,Mao Baoling,et al.Department of Instisute of Respiratory Disease,Xingqiao Hospital,Third Military Medical University,Chongqing 400037,China [;Effects of nuclear factor-κB activation on acute lung injury[J];Journal of Emergency Medicine;2003-09
3 Lu Yi;Pan Huazhen; Xu Caimin (Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China).;Oxidative Stress induced Apoptosis[J];PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS;1996-02
4 LI Wen-jun , YANG Zong - cheng , JI Tian - peng, YANG Xiao-dong,ZHANG Hong,ZHANG Bin, LI Er-hong, ZHAO uang-he. Burn center, 159th Hospital of PLA, Zu Ma Dian city, 463000; Henan province; Institate of Burn Research, Xi;Effects of LPS and dexamethasone on NF_(-k)B activation in cultured rat alveolar macrophages[J];Journal of Cellular and Molecular Immunology;2002-01
5 ZHANG Cheng, SHENG Zhi-Yong, HU Sen, et al. (Department of Burns and Plastic Surgery, Lanzhou General Hospital, 730050, China);Influence of enterocyte apoptosis on intestinal permeability after delayed resuscitation in scalded rats[J];Medical Journal of National Defending Forces In Northwest China;2004-01
6 Wei Zhi-gang, Zhang Xia, Lu Han-bing, Guo Jing Department of Neurology,Xuzhou Municipal Central Hospital, Xuzhou 221000, Jiangsu Province, China;Expression of Caspase-3 in rats with multiple organ dysfunction syndrome caused by focal cerebral ischemia-reperfusion[J];Chinese Journal of Clinical Rehabilitation;2006-28
7 Zhu Tuanjie, Zhai Zhimin, Xu Jing (ICU Room, Anhui Provincial Hospital, Hefei 230001);Leukocyte apoptosis in the patients with multiple system organ failure[J];Acta Universitis Medicinalis Nahui;2001-04
8 Lin Ling,Fang Lizheng,Wang Qi.ICU,Sir Run Run Shaw Hospital,Zhenjiang University,Hangzhou 310016,China;Neutrophil apoptosis in peripheral blood for severe acute pancreatitis and multiple organ dysfunction syndrome[J];Chinese Journal of Practical Surgery;2003-09
9 SONG Yong, MAO Baoling, QIAN Guisheng, et al Department of Respiratory Medicine, Nanjing General Hospital of Nanjing Command, Nanjing 210002, China;Effects of dexamethasone on apoptosis and expression of Fas/FasL system in lung tissues of ALI rats[J];CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES;2000-01
10 CAI Enqi, CHEN Zhengtang, WU Weiling. Instisute of Respiratory Medicine of PLA, Xinqiao Hospital, Third Military Medical University, Chongqing 400037;The effects of Lipopolysaccharide and antiinflammatory drugs on nuclear factorB in pulmonary intravascular macrophage[J];CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES;1999-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved