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《Journal of Nanjing University of Traditional Chinese Medicine》 2001-02
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Effect of Baoshen Tablet on Plasma ET-1, TXB_2 and 6-keto-PGF_(1α) of Rats with Chronic Renal Failure

NI Bin 1, ZHONG Yu 1, WANG Gang 2 ( 1Graduate students of Nanjing University of Traditional Chinese Medicine; 2Renal departmernent,Affiliated Hospital of Nanjihg University of Traditional chinese Medicine,Nanjing, Jiangsu Province, 210029,China)  
OBJECTIVE To observe the effect of Baoshen Tablet on plasma ET 1, TXB 2 and 6 keto PGF 1α in rats with chronic renal failure induced by adenine and to investigate into its clinical significance. METHOD The rats were divided randomly into groups and were given the medicine. Blood was obtained from the orbit and detected for the contents of plasma ET 1, TXB 2 and 6 keto PGF 1α and comparisons were made between the groups. RESULT The ET 1 level in the large dosage group was markedly lower than that in the pathology control group TXB 2 Level and . the ratio of TXB 2 to 6 keto PGF 1α in all treatment groups Were both markedly lower than that in the pathology control group.CONCLUSION the Chinese medicine Baoshen Tablet can regulate the body's hormone level, improve hemodynamics, inhibit cell proliferation and improve the function of tubule, thus protecting the kidney.
【Fund】: 江苏省科委九五攻关课题 !(BE960 5 3 )
【CateGory Index】: R277.5
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【Co-citations】
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1 LING Guang-hui 1, PENG You-ming 1,* , WANG Hai-tao 2, DUAN Shao-bing 1,LIU Ying-hong 1,LIU Fu-you 1 (1.Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha 410011, China 2.Department of Nephrology, Liu Hua Qiao Hospital, GuangZhou 510010, China);Depression of mPGEs expression by troglitazone in human renal glomerulus induced by high glucose and LPS[J];;2004-03
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【Secondary References】
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1 LONG Ruoting,HE ZeyunYiyang Health School,Yiyang (410000);The Study the Effects of Yishen Tang on Pathological Changes and Col-Ⅳ and MMP-2 Expression with 5/6 Nephrectomy Rats[J];Chinese Journal of Integrated Traditional and Western Nephrology;2006-06
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