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Comparison of Anti-asthma Effect for Guinea Pigs between Semen Sinapis Albae Liniment and Traditional Preparations

WANG Yin-ping1,XU Yue-hong2,WANG Dong-mei2,CHEN Bao2(1First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu, 210029,China;2Pharmacology College of Zhongshan University,Guangzhou,Guangdong,510045,China)  
OBJECTIVE To investigate into the effect of Semen Sinapis Albae Liniment in the treatment of guinea pig asthma,compared with traditional preparations.METHOD Egg albumen was used to create guinea pig asthma models.Semen Sinapis Albae Liniment produced with modern pharmacological methods was applied to the back of the guinea pigs.RESULT The liniment could markedly prolong asthma incubation period,relieve the severity of asthma attack,shorten the duration of asthma and improve the pathological state of the lung tissue.However,the traditional preparations were superior to the liniment in the initial inducement of the incubation period of asthma attack.CONCLUSION Semen Sinapis Albae Liniment has good effect in preventing and controlling the attack of experimental asthma and reducing the severity of the attack.Though further researches are necessary,it already shows its advantages in the preparation form,which are worth studying and applying.
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