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《Journal of Critical Care in Internal Medicine》 2012-02
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Influence of age on the left ventricular ejection fraction in patients with acute ST-segment elevation myocardial infarction

ZHAO Rui-fu,LIU Yang,XIE Han,WAN De-li,JIN Guo-zhu,WANG Lin.Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030,China  
Objective:To analyze the influence of age on the left ventricular ejection fraction (LVEF) in patients with acute ST-segment elevation myocardial infarction(STEMI).Methods:A total of 245 patients with acute STEMI were divided into 5 groups according to age:group 1 (≤50 years old,n=49),group 2 (51~60 years old,n=70),group 3 (61~70 years old,n=62),group 4 (71~79 years old,n=50),group 5(≥80years old,n=14).Baseline parameters such as age,gender, history of hypertension,diabetes,hyperlipidemia and smoking,the number of ST segment elevation leads of hyperacute and acute STEMI,cTnI levels,Killip classification,LVEF,receiving PCI or not and hospital mortality were compared and analyzed.Results:Multiple linear regression analysis showed that LVEF were negatively correlated with age and cTnI levels (P0.05).The LVEF were decreased with the increase of age and cTnI levels.The average LVEF were significantly higher in group 1 than any other groups (P0.05),while the average LVEF were significantly lower in group 5 than any other groups (P0.05).Ratio of Killip classification (class Ⅱ、Ⅲ、Ⅳ) were significantly higher in group 5 than any other groups (P0.05).The hospital mortality was significantly higher in group 5 than that in group 1,group 2 and group 3 (P0.05).Conclusion:Age is an independent risk factor in patients with acute STEMI.
【CateGory Index】: R542.22
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 WANG Chong-hui~*, HUANG Rui, FANG Quan, ZHANG Shu-yang, SHEN Zhu-jun, FAN Zhong-jie, JIN Xiao-feng, XIE Hong-zhi, LIU Zhen-yu.*Department of cardiology, Peking Union Medical College Hospital, Beijing, 100730, China;Influence of age on clinical outcomes of primary percutaneous coronary intervention in elderly patients with acute ST-segment elevation myocardial infarction[J];Chinese Journal of Cardiovascular Medicine;2010-03
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 Li Xiaotong(Clinical Medical College of Yangzhou University,Jiangsu 225001 China);Nursing care of medication in coronary artery interventional therapy in emergency Department[J];Chinese Nursing Research;2012-09
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 ZHANG Lixin MA Changsheng ZHANG Haibin GAO GuobinGUO Jincheng ZHANG Zhenghai ZHANG Xuekun(Department of Cardiology, Luhe Hospital,Tongzhou District,Beijing,101149,China);Effect of primary percutaneous coronary intervention on outcomes in elderly patients with acute ST elevation myocardial infarction[J];Journal of Clinical Cardiology;2007-04
2 MA Genshan, CHEN Zhong, FENG Yi, et al Department of Cardiology, the Affiliated ZhongDa Hospital of Southeast University, Nanjing 210009, China;Primary percutaneous coronary intervention in patients with acute myocardial infarction over eighty years old[J];Chinese Journal of Interventional Cardiology;2004-06
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