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《Acto andrologica Sinica》 2004-06
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Effects of Reproductive Hormones on Spermatogenesis

Cui Yugui,Chen Ziqing,Sha Jiahao Key Laboratory,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China(Cui YG,Chen ZQ);Key Reproductive Laboratory of Jiangsu Province,Nanjing,Jiangsu 210029,China(Sha JH)  
Spermatogenesis,a continuous course of cell proliferation and differentiation,depends on reproductive hormones. FSH and LH-induced T are the main hormones regulating spermatogensis. Intratesticular T is one of the key factors in maintaining spermatogenesis,while FSH is just as important for origination and maintenance of normal spermatogenesis. Sertoli cells are the pivot of hormonal regulation. Interestingly,these reproductive hormones also regulate sperm cell apoptosis in normal spermatogenesis. Further studies on the hormonal regulation of spermatogenesis provide a base for the development of safe and recoverable contraceptives for males.
【Key Words】： spermatogenesis gonadotropin androgen
【Fund】： 江苏省 13 5重点医学人才项目 (RC2 0 0 2 0 76)
【CateGory Index】： R321.1
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