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《National Journal of Andrology》 2009-09
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Dexketoprofen Trometamol in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

JIANG Ming-hua,WU Guan-cheng,LIU Hong-liangDepartment of Venereology,Hengli People's Hospital,Dongguan,Guangdong 523460,China  
Objective:To evaluate the clinical efficacy and safety of dexketoprofen trometamol in the treatment of patients with chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS). Methods: A total of 115 patients with CP/CPPS were divided into a dexketoprofen trometamol group (n=40),treated with dexketoprofen trometamol (25 mg,tid) and terazosin (2 mg,qn),an indometocin group (n=40) given indometocin (25 mg,tid) and terazosin (2 mg,qn),and a terazosin group (n=35) administered terazosin (2 mg,qn ) only,all treated for 4 weeks. Scores on the NIH-chronic prostatitis symptom index (NIH-CPSI) were obtained before and after the treatment,and the efficacy and adverse events were observed and compared. Results: The NIH-CPSI scores were significantly improved after the treatment in all the three groups. The clinical efficacy was significantly better in the dexketoprofen trometamol and indometocin groups than in the terazosin group (P 0.05),but with no significant difference between the former two (P 0.05). The rates of adverse events were 10.00%,18.57% and 27.50% in the dexketoprofen trometamol,terazosin and indometocin groups,significantly lower in the former two than in the latter one (P 0.05). Conclusion: The combination of dexketoprofen trometamol with terazosin could effectively improve the clinical symptoms of CP/CPPS,better than terazosin in therapeutic efficacy and than indometocin in drug tolerance.
【CateGory Index】: R697.33
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【References】
Chinese Journal Full-text Database 1 Hits
1 XU Yong(The Firsr Affiliated Hospital of University of South China, Hunan Hengyang 421001,China);The Research of Terazosin Hydrochloride Combined with Diclofenac Sodium in Treatment of CP / CPPS[J];现代临床医学;2012-03
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Yang Ming-gen , Zhao Xiao-kun , Wang Xin-jun Department of Urology, The Second Xiangya Hospital, Central South University, Changsha 410011, China;Management of Chronic Prostatitis(CP) in China:A Meta-analysis of Randomized Controlled Trials(RCTs)[J];中国循证医学杂志;2007-10
2 YANG Xiao yan 1,GONG Pei li 1,SHEN Lin 2,HU Yong hong 3,,LIU Pei lin 3 (1 Institute of Clinical Pharmacology,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;2 Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;3 Tongji Hospital,Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030,China);Comparative study on the safety and efficacy of dexketoprofen trometamol and ketoprofen in treatment of rehumatoid[J];中国新药杂志;2003-04
【Co-citations】
Chinese Journal Full-text Database 9 Hits
1 LING Sa;LIANG Lu;DAI Zhengling;ZHANG Zhouju;ZHONG Qiaoni;Hubei Pharmaceutical Industry Research Institute Co., Ltd.;;Determination of N-Octyl-D-glucamine in Dexketoprofen Trometamol Injection by HPLC-ELSD[J];中国医药工业杂志;2015-11
2 HU Jie;HOU Jing-yu;LU Yuan;HUANG Yong;LI Yong-jun;ZHENG Lin;School of Pharmacy,Guiyang Medical College;Guizhou Provincial Key Laboratory of Pharmaceutics;Engineering Research Center for the Development and Application of Ethnic Medicine and TCM(Ministry of Education);;Pharmacokinetics and bioequivalence of the dexketoprofen trometamol sustained-release tablets in Beagle dogs[J];沈阳药科大学学报;2015-08
3 XIE Chun-yu;QIU Yong-chao;MCH Hospital of Shaoguan;The First Affiliated Hospital of Guangzhou Chinese Medicine University;;Clinical Observation of Prostate Decoction in the Treatment of Ⅲ Type Prostatitis Syndrome of qi Stagnation and Blood Stasis[J];中国医药指南;2015-08
4 LIU Li-jun;ZHANG Jie;TANG Li;LIU Yue;HUANG Yong;School of Pharmacy,Guiyang Medical College,Engineering Research Center for the Development and Application of ethnic Medicines and TCM,Ministry of Education;Provincial Key Laboratory of Pharmaceutics in Guizhou Province;;Preparation of injection of dexketoprofen tromethamine thermosensitive hydrogel and study on its in vitro release[J];中国医院药学杂志;2013-22
5 LI Hai-song, LI Yue-qing, LIU Fu-ding, HAN Fu-lu, CHEN Wang-qiang, WANG Bin, YANG Jie (Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700);Umbilical therapy combined with suppository for treating syndrome of qi stagnation and blood stasis of type Ⅲ prostatitis[J];北京中医药大学学报(中医临床版);2010-04
6 JIANG Ming-hua,WU Guan-cheng,LIU Hong-liangDepartment of Venereology,Hengli People's Hospital,Dongguan,Guangdong 523460,China;Dexketoprofen Trometamol in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome[J];中华男科学杂志;2009-09
7 JIANG Ming-hua1,LU Dong-qing2(1 Department of Dermatology,Hengli People's Hospital,Dongguan 523460,China;2 Department of Dermatology,The Fifth Affiliated Hospitalof Sun Yat-sen University,Zhuhai 519000,China);Therapeutical Observatiun of Dexketoprofen Trometamol in Herpes zoster Pain Syndrome[J];中国皮肤性病学杂志;2009-06
8 DU Chun-xia (Fuxing Hospital,Capital Medical University,Beijing 100038);Overview on clinical application of ketoprofen[J];安徽医药;2007-10
9 MA Biao~1 ZHANG Ning~1 WANG Feng-shan~2 (1.Saisheng Pharmaceutical Co.,Ltd,Beijing 100176,China; 2.School of Pharmaceutical Science,Shandong University,Jinan 250012,China);Overview on Clinical Application of Ketoprofen[J];食品与药品;2007-04
【Co-references】
Chinese Journal Full-text Database 1 Hits
1 JIANG Ming-hua,WU Guan-cheng,LIU Hong-liangDepartment of Venereology,Hengli People's Hospital,Dongguan,Guangdong 523460,China;Dexketoprofen Trometamol in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome[J];中华男科学杂志;2009-09
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 ZHAO Jun-feng;GONG Yan-ling;ZHAO Li-jie;Clinical laboratory, Laoting County Hospital;;Clinical observation of biofeedback electrical stimulation combined with drug in treatment of Ⅲ prostatitis[J];中国医学装备;2015-11
2 Xu Guangyu;Meng Qingrong;Chen Kai;Department of Urology,People's Hospital of Laiwu City;;Effect of Roxithromycin Sustained Release Capsules Combined with Tamsulosin in the Treatment of Category Ⅲa Prostatitis[J];中国药师;2014-08
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 YE Zhang-qun~(1),LAN Ru-zhu~(1),WANG Shao-gang~(1),CAI Song-liang~(2),CHEN Ge-ming~(2),LI Ning-chen~(3),SONG Yi~(3),NA Yan-qun~(3)1.Department of Urology,Tongji Hospital Affiliated to Tongji Medical College,Huazhong University of Science & Technology,Wuhan,Hubei 430030,China; 2.Department of Urology,the First Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou,Zhejiang 210003,China;3.Insitute of Urology,Peking University First Hospital,Beijing 100034,China;A Clinical Study of Prostat Combined with an Antibiotic for Chronic Nonbacterial Prostatitis[J];中华男科学杂志;2006-09
2 XI Qi-lin, WANG Shao-gang, LIU Ji-hong, et al(Department of Urology,Tongji Hospital,Huazhong University of Science and Technology,Wuhan,430030,China);The Efficacy and Safety of Prostat in the Treatment of Chronic Nonbacterial Prostatitis:A Randomized,Double-blind,Placebo-controlled Clinical Trial[J];医学临床研究;2006-03
3 Wang Wei, He Huixu, Hu Weilie, Zhang Xiaoming, Wang Yuanli Department of Urology, Guangzhou General Hospital of Guangzhou Command, PLA, Guangzhou, Guangdong 510010, China(Wang W, He HX, Hu WL, Zhang XM, Wang YL);Efficacy and Safety of Intraprostatic Injection of Chuanshentong for Chronic Abacterial Prostatitis/Chronic Pelvic Pain Syndrome[J];中华男科学;2004-03
4 LV Ming;ZHAO Sheng-tian;WANG Shu-mei;SHI Ben-kang; FAN Yi-dong;WANG Jie-zhen Depatment of Clinical Epidemiology, Qilu Hospital, Shandong University, Jinan 250012, China;Alpha-blockers and bioflavonoids in men with chronic nonbacterial prostatitis (NIH-Ⅲa):a prospective,placebo-controlled trial[J];中华流行病学杂志;2004-02
5 LI Ning-chen*,ZHANG Kai,XIAO He,et al. *Department of Urology,First Hospital,Institute of Urology,Peking University,Beijing 100034,China;The efficacy and safety of Prostant ~(TM) in the treatment of chronic prostatitis: a multi-center,randomized,double-blind,placebo-controlled clinical trial[J];中华泌尿外科杂志;2003-11
6 XU Gang *,LU Jun,TANG Xiaoda,et al. *Department of Urology,Huashan Hospital,Fudan University,Shanghai 200040,China;The efficacy and safety of Prostant~(TM) in the treatment of chronic prostatitis:a multi center, randomized, double blinded, placebo controlled trial[J];中华泌尿外科杂志;2002-05
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