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Several Natural Polysaccharide Lowering Blood Lipid of Research

XIN Dan-dan,BO Geriletu,Narisu,Zhaorigetu(Inner Mongolia Autonomous Region Mongolian Chemical Key Laboratories, Inner Mongolia University,Hohhot 010021,China)  
AIM: To compare the lowering blood lipid for astragalus polysaccharides(APS),glycyrrhiza polysaccharide(GPS),platycodon polysaccharide PPS(J) and polygonatum polysaccharide PPS(Y).METHODS: Seventy healthy male rats were randomly divided into seven groups: blank control group(fed with common feed),high lipid model group(main component: 3% cholesterol,10% lard,0.5% cholic acid sodium and 86.5% based feed),positive control group(this experiment with simvastatin as the positive control medicine),astragalus polysaccharides(APS) group,glycyrrhiza polysaccharide(GPS) group,platycodon polysaccharide,PPS(J) group and polygonatum polysaccharide PPS(Y) group;blank group continue to feed the based feed,other six groups feed fatty feed 20g/day,after 15d,levels and contents of total cholesterol(TC),triglyceride(TG) in serum and levels of high density lipoprotein cholesterol(HDLC) and low density lipoprotein cholesterol(LDLC) were detected.The result shows that astragalus polysaccharides,Platycodon polysaccharide and Polygonatum Polysaccharide have significantly reduced blood lipid,and liquorice polysaccharide on serum all the indexes have no effect.
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