Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Animal Husbandry and Feed Science》 2010-02
Add to Favorite Get Latest Update

Epigenetics in Tumor

XU Shuo-qi(Experimental Center of Life Science,Nanjing Agricultural University,Nanjing 210095,China)  
As a branch of genetics,epigenetics is relative to the inheritable expression change of gene or protein,without altered gene sequence,its research objective is gene modification,including DNA methylation,histone acetylation,gene marker and so on.In the recent years,with the studying development,the application on curing tumor has been achieved success in DNA methyltransferase and histone acetyltransferases inhibitors.Here we reviewed the mechanisms of the above mentioned epigenetic modification,their roles in tumor initiation,and the progresses in tumors therapies.
【Fund】: 南京农业大学生命科学实验中心开放课题基金(680810150)
【CateGory Index】: R730.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 10 Hits
1 SUN Yong-jian et al (Department of Agronomy,Tianjin Agricultural University,Tianjin 300384);Molecular Mechanisms of Epigenetics and Its Advances[J];Journal of Anhui Agricultural Sciences;2008-33
2 Li Yan, Liang Qianjin, Tao Wei (College of Life Sciences, Beijing Normal University, Beijing 100875) (College of Life Sciences, Peking University, Beijing 100871);The methylation modification accompanying X chromosome inactivation[J];Chinese High Technology Letters;2007-12
3 YU Li (Department of Bio-chemistry,Baoshan College,Baoshan,Yunnan 678000);Study and Development of Epigenetics[J];Journal of Anhui Agricultural Sciences;2010-02
4 ZHOU Rong-rui,LI Jiang. (Dept. of Oral Pathology,The Ninth People′s Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200011,China);Histone acetylation and malignant tumors of head and neck[J];International Journal of Stomatology;2007-06
5 LAN Fei1 & SHI Yang 2 1 Department of Biology, Constellation Pharmaceuticals, 148 Sidney Street, Cambridge, MA 02139, USA 2 Department of Pathology, Harvard Medical School, 77 Ave Louise Pasteur, Boston MA, 02115, USA;Epigenetic regulation: methylation of histone and non-histone proteins[J];中国科学(C辑:生命科学)(英文版);2009-04
6 LIU Chun- Yan, SUN Hai- Jing, LU Jun, HUANG Bai- Qu ** (Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China);Histone Acetylation and Cancer[J];Progress In Biochemistry and Biophysics;2003-01
7 LU Rong,FANG Jing-Yuan*(Shanghai Institute of Digestive Disease,Shanghai Jiaotong University Medical School,Renji Hospital,Shanghai 200001,China);Epigenetic modification and cancer[J];Chinese Bulletin of Life Sciences;2006-01
8 BAI Juan,LIU Ji-yan,ZHENG Ling Department of Oncology,Chengdu Railway Center Hospital,Chengdu 610081,China.;Advances in the anticancer effect of histone deacetylase inhibitor[J];Journal of Modern Oncology;2009-06
9 WANG Yasong, JIN Yongtang School of Public Health,Anhui Medical University,Hefei 230032,China;Research progress on epigenetics of lung cancer[J];Journal of Hygiene Research;2007-01
10 Jing De ZHU1,2,*1The State-key Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiaotong University, LN 2200/25, Xietu Road, Shanghai 200032, China.2The Collage of Life Sciences, Zhejiang Science and Technology University, Xiasha University District, Hangzhou, Zhejiang 310018, China.;The altered DNA methylation pattern and its implications in liver cancer[J];细胞研究(英文版);2005-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 TENG Li-Juan, LI KeDepartment of Molecular Epidemiology, Medical College, Shantou University, Shantou, Guangdong, 515041, P. R. China;Research Progress on the Relationship between Nutrition and Cancer Epigenetics——Histone Modification Mechanisms[J];Chinese Journal of Cancer;2007-09
2 WANG Jun-Li1, ZHANG Hui-Zhong2, BAI Wan-Sheng1, LIU Li2, BIAN Ka1, CHENG Shi-Yin11Department of Otorhinolaryngology, 2Department of Clinical Laboratory, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China;Promoter hypermethylation and mRNA expression of TSLC1 gene in laryngeal squamous cell carcinoma[J];Journal of the Fourth Military Medical University;2007-07
3 WANG Min,LIU Wei,YANG Ai-Jun,WANG Chen-Yu,LI MinInstitute of Pathology,School of Basic Medicine,Lanzhou University,Lanzhou 730000,China;Expressions of vWF and HDAC1 and their effects on adhesion,invasion and motility in human gastric cancer cell line BGC-823 in vitro[J];Journal of the Fourth Military Medical University;2008-07
4 YU Li (Department of Bio-chemistry,Baoshan College,Baoshan,Yunnan 678000);Study and Development of Epigenetics[J];Journal of Anhui Agricultural Sciences;2010-02
5 TENG Li-juan,ZHANG Chang-song reviewing,LI Ke checking(Department of Molecular Epidemiology,Shantou University Medical College,Shantou 515041,Guangdong,China);Relationship of nutrition with cancer and its epigenetic DNA methylation mechanism[J];Journal of Medical Postgraduates;2008-01
6 ZHENG Xiao-mei,WU Ning-feng(Biotechnology Research Institute,Chinese Academy of Agricultural Sciences,Beijing 100081,China);Biological Function of DNA Methylation[J];Journal of Agricultural Science and Technology;2009-01
7 ZHOU Shui-gen1, SUN Ying-hao2, GAO Jian-ping11.Department of Urology, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing, Jiangsu 210002, China; 2.Department of Urology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China;DNA Methylation and Prostate Cancer[J];National Journal of Andrology;2007-12
8 GE Yong-li,YAN Xiao-hong (Department of Cell Biology,Inner Mongolia Medical College,Huhhot 010059 China);Relationship Between Survivin Gene and Colorectal Cancer[J];Inner Mongolia Medical Journal;2008-01
9 CHANG ZengYi School of Life Sciences, Peking University, Beijing 100871, China;Launching the CUSBEA Article Series in SCIENCE CHINA Life Sciences[J];中国科学:生命科学(英文版);2010-04
10 PENG Guo,DAI Dong-qiu Department of Oncology Surgery,First Affiliated Hospital,China Medical University,Shenyang 110001,P.R.China;Development in research on histone acetylation and methylation in alimentary canal neoplasms[J];Chinese Journal of Cancer Prevention and Treatment;2007-24
China Proceedings of conference Full-text Database 1 Hits
1 Yang Jian-ping,Zhuang Zhi-xiong,Hu Gong-hua, Zhang Jin-zhou,Wu Li-ming,et al. School Of Public Health,SUN Yat-sen University,Guangzhou,510080,China;Trichloracetic Acid Induced the Hepatic L-02 Cells Proliferation and DNA Hypomethylation in Human Hepatic L-02 cells[A];[C];2006
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 SUN Yong-jian et al (Department of Agronomy,Tianjin Agricultural University,Tianjin 300384);Molecular Mechanisms of Epigenetics and Its Advances[J];Journal of Anhui Agricultural Sciences;2008-33
2 WANG Shun qing *,HONG Wen de,PENG Ai hua,et al. *Department of Hematology,Guangzhuo First Municipal Peop les Hospital, Guangzhou 510180,P.R.China;Detection of the hypermethylation of calcitonin gene by polymerase chain reaction and its implication in some hematological malignancies[J];CHINESE JOURNAL OF CANCER;1999-06
3 BAI Zhi Yong 1, XU Guo Bin 2, WU Shu Lan 1 (1. Department of Hematology, 2. Department of Laboratory, the First Hospital, Beijing Medical University, Beijing 100034, China);Detection of DNA-methyltransferase activity of leukemia cells with radiology microassay[J];Journal of Beijing Medical University;2000-01
4 Li Zhuhua,Wang Shuren;The gene expression and regulation of epigenetics[J];Sichuan Journal of Physiological Sciences;2006-01
5 PENG En-lan1,TU Hong-yi2,CHEN Wei-min3(1.Department of Veteran,the 94th Hospital of PLA,Nanchang 330002,Jiangxi,China;2.Department of Pharmacy and Appliance,the 94th Hospital of PLA,Nanchang 330002,Jiangxi,China;3.College of Pharmaceutical Sciences,Jinan University,Guangzhou 510632,Guangdong,China);Epigenetics and Tumor[J];Life Science Research;2006-S1
6 YI Xia, SHANG Yong\|feng * (Department of Biochemistry and Molecular Biology, Oncology Center, Peking University Health Science Center, Beijing 100083, China);ATP-Dependent Physical Remodeling of Chromatin[J];Chinese Journal of Biochemistry and Molecular Biology;2003-04
7 He,Zhong-Xiao;Gu, Yu;Rao, Hong;Bai,Jian-Shi; Ma, Qing (Department of Biology, Beijing Normal University, Beijing 100875);The Effect of 5-Aza-2'-deoxycytidine (5-Aza-CdR)on Cell Differentiation and DNA Methylase of HL-60 Cells[J];;1995-04
8 ZHANG Yong-Biao, CHU Jia-You(Department of Genetics, Institute of Medical Biology, Peking Union Medical College, Kunming 650118, China);Progress of Research on Epigenetic and Human Disease[J];Hereditas(Beijing);2005-03
9 ZHANG Li-Li,WU Jian-Xin(Capital Institute of Pediatrics,Beijing 100020,China);DNA Methylation: An Epigenetic Mechanism for Tumorigenesis[J];Hereditas;2006-07
10 Qiu Dekai; Shen Lanlan; Fang Jingyuan; et al.(Shanghai Institute of Digestive Diseases, 200001);Change of total genomic DNA methylation level in human hepatocellular carcinoma[J];CHINESE JOURNAL OF DIGESTION;1997-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved