INFLUENCE OF EFFECTIVE COMPOSITION OF SEVERAL CHINESE METERIA MEDICA ON L615LEUKEMIA OF CSF
Yan Xiaohong DjngBo KongLi(Department of Cytochemistry)
By the experimental research of antitumor activation of CSF and effective composition ofChinesc materia medica:Ber,APS and AP,we found that Ber,APS and AP all have activity againsttumor,survival period of L615 leukemia mouse was prolonged from 6 d to 8.8d. When the mouse ofleukemia was only in jected with Cancer suppressor factor(CSF),the average days of survlval was 151.7. In combination with Ber, APS and AP, effect of antitumor showed more obviously, their average rate of life prolonged(ARLP) had been increased distinctly and reached to 4 589 %,but the “cure standard”was 300%. Meanwhile,the structure of tissue of each organs had almost reached to normal.In the No 19 Bj marker chromosome of leukemia had been disappeared、The result showed that Ber,APS and AP had effect of antitumor and Could provoke immune cells in mouse to release CSF and expressed stronger killer activity agaist tumor cells.Therefore,further research of effective composition of Chinese materia medlca in biological treatment of tumor will have important significance.